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T3754

Sigma-Aldrich

L-Tyrosine

≥98% (HPLC)

Synonym(s):

(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid, 3-(4-Hydroxyphenyl)-L-alanine

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About This Item

Linear Formula:
4-(HO)C6H4CH2CH(NH2)CO2H
CAS Number:
60-18-4
Molecular Weight:
181.19
Beilstein:
392441
EC Number:
200-460-4
MDL number:
MFCD00002606
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24900164
NACRES:
NA.26

product name

L-Tyrosine, reagent grade, ≥98% (HPLC)

grade

reagent grade

Quality Level

200

Assay

≥98% (HPLC)

form

powder

color

white to off-white

mp

>300 °C (dec.) (lit.)

solubility

1 M HCl: soluble 50 mg/mL

application(s)

detection

SMILES string

N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI

1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1

InChI key

OUYCCCASQSFEME-QMMMGPOBSA-N

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Application

L-Tyrosine has been used to prepare tyrosine solution for tyrosinase assay. It has also been used to assay pepsin activity.

Biochem/physiol Actions

L-Tyrosine is a non-essential amino acid with a polar side chain. It is utilized by cells to synthesize proteins that have a role in signal transduction. L-Tyrosine is a proteogenic amino acid that acts as a receiver of phosphate groups that are transferred by kinases.

Other Notes

Amino acid precursor of dopamine and other catecholamines

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Study of Physiochemical Parameters for Optimizing Tyrosinase Activity in Rhodococcus ruber C4 and Pseudomonas geniculata C7/C10
Sapna S. Ingle
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John W Hill
Chemistry for Changing Times (2016)
Verena Rahm et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(4), 546-550 (2014-02-26)
Low-grade gliomas (LGGs) may harbor malignant foci, which are characterized by increased tumor cellularity and angiogenesis. We used diffusion-weighted MR imaging (apparent diffusion coefficient [ADC]) and PET with the amino acid O-(2-(18)F-fluorethyl)-L-tyrosine ((18)F-FET) to search for focal changes of diffusion
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