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Merck
CN

T2500100

Trimyristin

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Glyceryl trimyristate, 1,2,3-Tritetradecanoylglycerol, Glycerol trimyristate, Trimyristin

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About This Item

Linear Formula:
[CH3(CH2)12COOCH2]2CHOCO(CH2)12CH3
CAS Number:
555-45-3
Molecular Weight:
723.16
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329826710
MDL number:
MFCD00036229
Beilstein/REAXYS Number:
1718242

Key Documents

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Product Name

Trimyristin, European Pharmacopoeia (EP) Reference Standard

InChI key

DUXYWXYOBMKGIN-UHFFFAOYSA-N

SMILES string

CCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC

InChI

1S/C45H86O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-43(46)49-40-42(51-45(48)39-36-33-30-27-24-21-18-15-12-9-6-3)41-50-44(47)38-35-32-29-26-23-20-17-14-11-8-5-2/h42H,4-41H2,1-3H3

grade

pharmaceutical primary standard

API family

trimyristin

manufacturer/tradename

EDQM

mp

56-57 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

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Application

Trimyristin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Knowledge about the release behavior and drug retention properties of colloidal carriers is of essential importance for quality control as well as to predict in vivo performance. When conducting release studies from such systems, the release media should preferentially contain
Kunal Jain et al.
Drug delivery, 22(7), 940-954 (2014-02-12)
The objective of the study was to optimize artemether-loaded nanostructured lipid carriers (ARM-NLC) for intranasal delivery using central composite design. ARM-NLC was prepared by microemulsion method with optimized formulation having particle size of 123.4 nm and zeta potential of -34.4
Prabagar Balakrishnan et al.
Pharmaceutical research, 33(1), 206-216 (2015-09-05)
To evaluate the anti-tumor effect of ceramide or trimethylphytosphingosine-iodide (TMP-I) containing solid lipid nanoparticles (SLNs) prepared using trymyristin, phosphatidylcholine (PC), and Pluronic P85 (P85) for intravenous delivery of docetaxel. Docetaxel-loaded SLNs using ceramide or TMP-I at 3.22% (w/w) with a
Krishnan Ganesh Prasath et al.
Journal of proteomics, 208, 103503-103503 (2019-08-28)
Candida albicans, a dimorphic opportunistic fungus is known to form robust biofilm and commonly associated with superficial and life threatening systemic infections. The repertoire of C. albicans infection is comprehensive due to its biofilm mediated virulence and occurrence of resistance
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