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SYNPLE-M001

Sigma-Aldrich

Reagent-cartridge Mitsunobu

Synple

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Synonym(s):
Synple 2
MDL number:
UNSPSC Code:
12161503
NACRES:
NA.22

Quality Level

parameter

≤0.5 mmol

General description

Reagent-cartridge Mitsunobu is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the dehydrative coupling of primary alcohols and a variety of pronucleophiles. The cartridge contains all necessary reagents to perform the Mitsunobu transformation. The Synple platform eliminates the tedious removal of the Ph3PO byproduct.

Scale: up to 0.5 mmol
Compatible alcohols: primary, secondary
Compatible nucleophiles: phenols, carboxylic acids, tosyl amides, hydrazones, phthalimides

Cartridge contents:
  • Supported triphenylphosphine
  • DTBAD (di-tert-butyl azodicarboxylate)
  • SCX (for purification)
  • Supported carbonate (scavenger)

Learn more about the Synple automated synthesis platform.

Features and Benefits of Synple Platform
  • Time savings - pre-installed protocols have been highly optimized, which obviates the need for the user′s own reaction development and optimization
  • Easy to use - protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
  • Safety - all chemicals are contained in the system, minimizing the user′s exposure
  • Set-up reaction in less than 5 minutes
  • Small footprint
  • Plug & Play system - simple installation
  • Reaction temperatures from 25 °C - 80 °C
  • Cartridges available for many different reactions
  • Prefilled with all required reagents
  • RFID chip containing optimized reaction protocol

Legal Information

Product of Synple Chem AG

related product

Product No.
Description
Pricing

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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