All Photos(1)
Synonym(s):
3,4,8,9-Tetaihydroxy-6H-dibenzo[b,d]pyran-6-one, 3,4,8,9-Tetrahydroxy-6H-benzo[c]chromen-6-one, 3,4,8,9-Tetrahydroxybenzo[c]chromen-6-one, 3,4,8,9-Tetrahydroxyurolithin, Uro D, Uro-D, UroD
Empirical Formula (Hill Notation):
C13H8O6
CAS Number:
Molecular Weight:
260.20
MDL number:
UNSPSC Code:
12352205
NACRES:
NA.77
Recommended Products
Assay
95% (HPLC)
Quality Level
form
solid
mp
>227 °C
storage temp.
2-8°C
InChI
1S/C13H8O6/c14-8-2-1-5-6-3-9(15)10(16)4-7(6)13(18)19-12(5)11(8)17/h1-4,14-17H
InChI key
NEZDQSKPNPRYAW-UHFFFAOYSA-N
General description
Urolithins are microflora human metabolites of dietary ellagic acid (EA) derivatives, such as ellagitannins (ETs). They are produced in the human gut, and found in urine in the form of urolithin B glucuronide after absorption of ellagitannins-containing food such as pomegranate, strawberries, red raspberries, walnuts or oak-aged red wine. During intestinal metabolism by bacteria, ellagitannins and punicalagins are converted to urolithins.
Application
Metabolomics research
Other Notes
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WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Adrián Cortés-Martín et al.
Journal of agricultural and food chemistry, 68(45), 12606-12616 (2020-11-03)
The maternal-infant transmission of several urolithins through breast milk and the gut colonization of infants by the urolithin-producing bacterium Gordonibacter during their first year of life were explored. Two trials (proof-of-concept study: n = 11; validation study: n = 30)
Kristen M Roberts et al.
Molecular nutrition & food research, 64(10), e1900800-e1900800 (2020-03-01)
Black raspberry (BRB) phytochemicals demonstrate anti-carcinogenic properties in experimental models, including prostate cancer. Two BRB foods, a confection and nectar, providing a consistent and reproducible product for human clinical studies are designed and characterized. Men with clinically localized prostate cancer
Francisco A Tomás-Barberán et al.
Molecular nutrition & food research, 61(1) (2016-05-10)
Urolithins are dibenzo[b,d]pyran-6-one derivatives that are produced by the human gut microbiota from ellagitannins and ellagic acid (EA). These metabolites are much better absorbed than their precursors and have been suggested to be responsible for the health effects attributed to
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