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S7795

Sigma-Aldrich

Sodium carbonate

BioXtra, ≥99.0%

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Synonym(s):
Calcined soda, Carbonic acid disodium salt, Soda ash
Linear Formula:
Na2CO3
CAS Number:
497-19-8
Molecular Weight:
105.99
Beilstein:
4154566
EC Number:
207-838-8
MDL number:
MFCD00003494
UNSPSC Code:
12161700
PubChem Substance ID:
24899762
NACRES:
NA.21

product line

BioXtra

Quality Level

200

Assay

≥99.0%

form

powder

impurities

≤0.02% Phosphorus (P)
≤0.1% Insoluble matter

pH

11.2 (25 °C, 4 g/L)

mp

851 °C (lit.)

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.02%

cation traces

Al: ≤0.001%
Ca: ≤0.02%
Cu: ≤0.0005%
Fe: ≤0.001%
K: ≤0.005%
Mg: ≤0.005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

O=C(O[Na])O[Na]

InChI

1S/CH2O3.2Na/c2-1(3)4;;/h(H2,2,3,4);;/q;2*+1/p-2

InChI key

CDBYLPFSWZWCQE-UHFFFAOYSA-L

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General description

Sodium carbonate is usually referred to as soda ash. Solvay process uses sodium chloride and limestone to produce sodium carbonate. Sodium carbonate enhances the pretreatment of rice straw and enhances delignification process. Sodium carbonate finds its application in the extraction of bioactive metabolites like epoxyditerpenoids and alkaloids and removes acidic compounds from the extract. Sodium carbonate induces the phase separation in salt induced phase separation extraction (SIPSE) method and enhances the plasma partitioning with acetonitrile.

Application

Sodium carbonate has been used:
  • to stop α-glucosidase enzyme activity using the extract of Terminalia species
  • as a component in carbonate/bicarbonate buffer for enzyme linked immunosorbent assay (ELISA)
  • as a component in the growth medium for Synechocystis strains

Biochem/physiol Actions

Buffer component, may be used for the removal of peripheral membrane proteins.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sodium Carbonate: A Versatile Material (2000)
ELISA to evaluate plasma anti-asparaginase IgG concentrations in patients with acute lymphoblastic leukemia
Wang B, et al.
Journal of Immunological Methods, 239(1-2), 75-83 (2000)
Analysis of Metals in Whole Cells, Thylakoids and Photosynthetic Protein Complexes in Synechocystis sp. PCC6803
Gandini C, et al.
Bio-protocol, 8(12), e2889-e2889 (2018)
Eduardo Isanta et al.
Water research, 80, 149-158 (2015-05-23)
Partial nitritation for a low-strength wastewater at low temperature was stably achieved in an aerobic granular reactor. A bench-scale granular sludge bioreactor was operated in continuous mode treating an influent of 70 mg N-NH4(+) L(-1) to mimic pretreated municipal nitrogenous
Kun-Hui Lu et al.
Journal of leukocyte biology, 98(3), 301-311 (2015-05-23)
Understanding the molecular mechanisms regulating T cell reactivity is required for successful reprogramming of immune responses in medical conditions, characterized by dysfunctions of the immune system. Nck proteins are cytoplasmic adaptors mediating diverse cellular functions, including TCR signaling. By enhancing
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