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S6689

Sigma-Aldrich

SynaptoRed C2

≥95% purity (HPLC), solid

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Synonym(s):
FM4-64, N-(3-Triethylammoniopropyl)-4-(6-(4-(diethylamino)phenyl) hexatrienyl)pyridinium dibromide, Pyridinium, 4-[6-[4-(diethylamino)phenyl]- 1,3,5-hexatrienyl]-1-[3-(triethylammonio) propyl]-, dibromide
Empirical Formula (Hill Notation):
C30H45Br2N3
CAS Number:
Molecular Weight:
607.51
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

Quality Level

Assay

≥95% (HPLC)

form

solid

color

deep purple

solubility

DMSO: 10 mg/mL

εmax

≥37 at 538-548 nm in methanol

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

[Br-].[Br-].CCN(CC)c1ccc(/C=C\C=C\C=C/c2cc[n+](CCC[N+](CC)(CC)CC)cc2)cc1

InChI

1S/C30H45N3.2BrH/c1-6-32(7-2)30-20-18-28(19-21-30)16-13-11-12-14-17-29-22-25-31(26-23-29)24-15-27-33(8-3,9-4)10-5;;/h11-14,16-23,25-26H,6-10,15,24,27H2,1-5H3;2*1H/q+2;;/p-2

InChI key

AFVSZGYRRUMOFH-UHFFFAOYSA-L

General description

SynaptoRed C2 is an amphiphilic styryl dye. It stains endocytic intermediates and vacuole membranes.

Application

SynaptoRed C2 has been used for propidium iodide (PI) blockage.

Biochem/physiol Actions

Fluorescent dye suitable for monitoring synaptic activity at neuromuscular junctions.

Legal Information

SynaptoRed is a trademark of Biotium, Inc.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Magdalena Plotka et al.
Viruses, 11(7) (2019-07-22)
Bacteria that thrive in extreme conditions and the bacteriophages that infect them are sources of valuable enzymes resistant to denaturation at high temperatures. Many of these heat-stable proteins are useful for biotechnological applications; nevertheless, none have been utilized as antibacterial
Plant Cell Expansion: Methods and Protocols (2014)
R. W. Sabnis
Handbook of Biological Dyes and Stains: Synthesis and Industrial Applications null
Construction of a functional Casparian strip in non-endodermal lineages is orchestrated by two parallel signaling systems in Arabidopsis thaliana
Li P, et al.
Current Biology, 28(17), 2777-2786 (2018)
B Wendland et al.
The Journal of cell biology, 135(6 Pt 1), 1485-1500 (1996-12-01)
A complete understanding of the molecular mechanisms of endocytosis requires the discovery and characterization of the protein machinery that mediates this aspect of membrane trafficking. A novel genetic screen was used to identify yeast mutants defective in internalization of bulk

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