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S4641

Sigma-Aldrich

Sodium citrate tribasic dihydrate

ACS reagent, ≥99.0%

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Synonym(s):
Citric acid trisodium salt dihydrate, Trisodium citrate dihydrate
Linear Formula:
HOC(COONa)(CH2COONa)2 · 2H2O
CAS Number:
6132-04-3
Molecular Weight:
294.10
Beilstein:
6104939
EC Number:
200-675-3
MDL number:
MFCD00150031
UNSPSC Code:
12352100
PubChem Substance ID:
24899613
NACRES:
NA.21

grade

ACS reagent

Quality Level

200

Agency

suitable for SM 4500 - NH3

Assay

≥99.0%

impurities

≤0.003% Ammonia (NH3)
≤0.005% Insoluble matter

pH

7.0-9.0 (25 °C, 5% in solution)

mp

>300 °C (lit.)

solubility

water: soluble 29.4 g/L at 20 °C (completely)

anion traces

chloride (Cl-): ≤0.003%
sulfate (SO42-): ≤0.005%

cation traces

Ca: ≤0.005%
Fe: ≤5 ppm
heavy metals: ≤5 ppm (by ICP-OES)

SMILES string

O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3

InChI key

NLJMYIDDQXHKNR-UHFFFAOYSA-K

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Application

Sodium citrate tribasic dihydrate can be used as a catalyst to synthesize:     
  • Fused O- and N-heterocyclic derivatives via multicomponent Knoevenagel-cyclocondensation of isatin/aldehyde/ acenaphthylene-1,2-dione, malononitrile, and various C−H activated acids.     
  • Chromeno[3′,4′:5,6]pyrano[2,3-d]pyrimidines by the condensation reaction of 4-hydroxycoumarin, aromatic aldehydes, and barbituric acid/thiobarbituric acid.

It can also be used as:      
A reducing agent to synthesize metal nanoparticles via sol-gel method using corresponding metal salt precursors.    
A controlling agent in the synthesis of single-crystal of coordination polymer [Co(H2O)2Ni(CN)4 4H2O].

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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