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S2054

Sigma-Aldrich

Sodium gluconate

meets USP testing specifications

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Synonym(s):
D-Gluconic acid sodium salt, 2,3,4,5,6-Pentahydroxycaproic acid sodium salt, D-Gluconate sodium salt, Sodium D-gluconate
Empirical Formula (Hill Notation):
C6H11NaO7
CAS Number:
527-07-1
Molecular Weight:
218.14
Beilstein:
3919651
EC Number:
208-407-7
MDL number:
MFCD00064210
UNSPSC Code:
12352201
PubChem Substance ID:
24899510
NACRES:
NA.21

biological source

microbial

Quality Level

200

Agency

USP/NF
meets USP testing specifications

form

solid

color

beige

useful pH range

6.5 - 7.5

mp

170-175  °C

solubility

590 g/L at 25 °C

application(s)

pharmaceutical (small molecule)

storage temp.

room temp

SMILES string

[Na+].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

InChI

1S/C6H12O7.Na/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1

InChI key

UPMFZISCCZSDND-JJKGCWMISA-M

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Application

Sodium gluconate has been used as a component of recording buffer used in two-electrode voltage-clamp (TEVC) recording in Xenopus laevis oocytes. It has also been used as a control for sodium.

Biochem/physiol Actions

Ingestion of sodium gluconate is known to stimulate the production of intestinal butyrate. It is widely used in food, pharmaceutical paper and textile industry. It acts as a chelating agent. Sodium gluconate serves as a detergent in bottle washing formulation.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Two-electrode voltage-clamp recordings in Xenopus laevis oocytes: reconstitution of abscisic acid activation of SLAC1 anion channel via PYL9 ABA receptor
Wang C, et al.
Bio-protocol, 7(2) (2017)
Dietary sodium gluconate protects rats from large bowel cancer by stimulating butyrate production
Kameue C, et al.
The Journal of Nutrition, 134(4), 940-944 (2004)
Gluconic acid: Properties, applications and microbial production.
Ramachandran S, et al.
Food Technology and Biotechnology, 44(2) (2006)
Influence of nitrate and nitrite on thyroid hormone responsive and stress-associated gene expression in cultured Rana catesbeiana tadpole tail fin tissue
Hinther A, et al.
Frontiers in Genetics, 3, 51-51 (2012)
Elena von Molitor et al.
Cell calcium, 87, 102164-102164 (2020-02-06)
Bridging the gap between two-dimensional cell cultures and complex in vivo tissues, three-dimensional cell culture models are of increasing interest in the fields of cell biology and pharmacology. However, present challenges hamper live cell imaging of three-dimensional cell cultures. These
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