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Merck
CN

S100

Mianserin hydrochloride

analytical standard, for drug analysis

Synonym(s):

1,2,3,4,10,14b-Hexahydro-2-methyl-dibenzo[c,f]pyrazino[1,2-a]azepine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C18H20N2 · HCl
CAS Number:
21535-47-7
Molecular Weight:
300.83
UNSPSC Code:
41116107
PubChem Substance ID:
329824190
EC Number:
244-426-7
MDL number:
MFCD00055072

Key Documents

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InChI key

YNPFMWCWRVTGKJ-UHFFFAOYSA-N

InChI

1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H

SMILES string

Cl.CN1CCN2C(C1)c3ccccc3Cc4ccccc24

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

solubility

H2O: 3.4 mg/mL, ethanol: 5.6 mg/mL

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Antidepressant; antagonist/inverse agonist at 5-HT2 serotonin receptors; also blocks the H1 histamine receptor and the α2 adrenoceptor.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Williams syndrome (WS), caused by a heterozygous microdeletion on chromosome 7q11.23, is a neurodevelopmental disorder characterized by hypersociability and neurocognitive abnormalities. Of the deleted genes, general transcription factor IIi (Gtf2i) has been linked to hypersociability in WS, although the underlying
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