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S0150000

Salbutamol sulfate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Salbutamol hemisulfate salt, α1-[(tert-Butylamino)methyl]-4-hydroxy-1,3-benzenedimethanol hemisulfate salt, Albuterol sulfate

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About This Item

Empirical Formula (Hill Notation):
C13H21NO3 · 0.5H2SO4
CAS Number:
51022-70-9
Molecular Weight:
288.35
MDL number:
MFCD00055200
UNSPSC Code:
41116107
PubChem Substance ID:
329824415
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

albuterol, salbutamol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

OS(O)(=O)=O.CC(C)(C)NCC(O)c1ccc(O)c(CO)c1.CC(C)(C)NCC(O)c2ccc(O)c(CO)c2

InChI

1S/2C13H21NO3.H2O4S/c2*1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;1-5(2,3)4/h2*4-6,12,14-17H,7-8H2,1-3H3;(H2,1,2,3,4)

InChI key

BNPSSFBOAGDEEL-UHFFFAOYSA-N

Gene Information

human ... ADRB2(154)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Salbutamol sulfate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

Y0000034

Salbutamol impurity G, European Pharmacopoeia (EP) Reference Standard

Y0000030

Salbutamol impurity B, European Pharmacopoeia (EP) Reference Standard

Y0000031

Salbutamol impurity F, European Pharmacopoeia (EP) Reference Standard

Y0000071

Salbutamol impurity D, European Pharmacopoeia (EP) Reference Standard

Y0000032

Salbutamol impurity I, European Pharmacopoeia (EP) Reference Standard

S0100000

Salbutamol, European Pharmacopoeia (EP) Reference Standard

Y0001186

Salbutamol impurity J, European Pharmacopoeia (EP) Reference Standard

Y0001288

Salbutamol sulfate for system suitability, European Pharmacopoeia (EP) Reference Standard

1012633

Albuterol sulfate, United States Pharmacopeia (USP) Reference Standard

1358784

Levalbuterol hydrochloride, United States Pharmacopeia (USP) Reference Standard

1012600

Albuterol, United States Pharmacopeia (USP) Reference Standard

1012644

Albuterol Related Compound A, United States Pharmacopeia (USP) Reference Standard

1012655

Albuterol Related Compound B, United States Pharmacopeia (USP) Reference Standard

1012689

Albuterol Related Compound E, United States Pharmacopeia (USP) Reference Standard

BP451

Salbutamol, British Pharmacopoeia (BP) Reference Standard

BP302

Salbutamol sulfate, British Pharmacopoeia (BP) Reference Standard

PHR1960

Salbutamol Impurity D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2040

Albuterol Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1961

Salbutamol Impurity G, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1962

Salbutamol impurity I, Pharmaceutical Secondary Standard; Certified Reference Material

BP712

Salbutamol aldehyde impurity, British Pharmacopoeia (BP) Reference Standard

BP192

2-tert-Butylamino-1-(4-hydroxy-3-methylphenyl)ethanol sulfate, British Pharmacopoeia (BP) Reference Standard

BP852

Salbutamol impurity B, British Pharmacopoeia (BP) Reference Standard

BP704

Salbutamol ketone impurity, British Pharmacopoeia (BP) Reference Standard

PHR2106

4-[2-[(1,1-Dimethylethyl)amino]ethyl]-2-methylphenol, Pharmaceutical Secondary Standard; Certified Reference Material

PHR9050

4-[2-(tert-Butylamino)-1-methoxyethyl]-2-(hydroxymethyl)phenol, reference material, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR9071

4-[2-[Benzyl(tert-butyl)amino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

1012564

Albuterol Related Compound I, United States Pharmacopeia (USP) Reference Standard

PHR2332

Methyl5-[2-[benzyl(tert-butyl)amino]acetyl]-2-hydroxybenzoate hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H317,H351,H361fd

Hazard Classifications

Carc. 2 - Repr. 2 - Skin Sens. 1

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

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B Padhukasahasram et al.
The pharmacogenomics journal, 14(4), 365-371 (2014-01-15)
Inhaled short-acting beta-agonist (SABA) medication is commonly used in asthma patients to rapidly reverse airway obstruction and improve acute symptoms. We performed a genome-wide association study of SABA medication response using gene-based association tests. A linear mixed model approach was
Ashley Woodcock et al.
Chest, 144(4), 1222-1229 (2013-07-13)
The combination of fluticasone furoate (FF), a novel inhaled corticosteroid (ICS), and vilanterol (VI), a long-acting β2 agonist, is under development as a once-daily treatment of asthma and COPD. The aim of this study was to compare the efficacy of
Huan Wang et al.
Biosensors & bioelectronics, 49, 14-19 (2013-05-28)
A multiplexed electrochemical biosensor has been developed for fast and sensitive detection of ractopamine (RAC), salbutamol (SAL) and clenbuterol (CLB) based on reduced graphene oxide (rGO) and silver-palladium alloy nanoparticles (AgPd NPs). In this paper, rGO with high conductivity was
Stephen P Peters et al.
The Journal of allergy and clinical immunology, 132(5), 1068-1074 (2013-10-03)
Tiotropium has activity as an asthma controller. However, predictors of a positive response to tiotropium have not been described. We sought to describe individual and differential responses of asthmatic patients to salmeterol and tiotropium when added to an inhaled corticosteroid
Marc L Decramer et al.
International journal of chronic obstructive pulmonary disease, 8, 53-64 (2013-02-05)
Inhaled long-acting bronchodilators are the mainstay of pharmacotherapy for chronic obstructive pulmonary disease (COPD). Both the twice-daily long-acting β(2)-adrenoceptor agonists (LABAs) salmeterol and formoterol and the once-daily LABA indacaterol are indicated for use in COPD. This review examines current evidence
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