Nicotine Related Compound A/EP Impurity A

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Anatabine is a blood-brain barrier penetrant minor alkaloid, a cholinergic agonist, isolated from Solanaceae plant family that exhibits anti-inflammatory properties. Apparently, anti-inflammatory properties of anatabine are partially mediated by inhibition of STAT3 and p65 NFkB phosphorylation. Anatabine decreases the transcription and protein synthesis of β-secretase (BACE-1), and appears to ameliorate experimental autoimmune thyroiditis and encephalomyelitis.

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.