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PHR1940

Supelco

Aspirin Impurity D

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
2-[[2-(Acetyloxy)benzoyl]oxy]benzoic acid, Acetylsalicylsalicylic acid, 2-Carboxyphenyl o-acetylsalicylate
Empirical Formula (Hill Notation):
C16H12O6
CAS Number:
530-75-6
Molecular Weight:
300.26
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to Ph. Eur. Y0001161

API family

aspirin

CofA

current certificate can be downloaded

packaging

pkg of 50 mg

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

InChI

1S/C16H12O6/c1-10(17)21-14-9-5-3-7-12(14)16(20)22-13-8-4-2-6-11(13)15(18)19/h2-9H,1H3,(H,18,19)

InChI key

DDSFKIFGAPZBSR-UHFFFAOYSA-N

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General description

Aspirin Impurity D is an impurity of the antiplatelet drug aspirin, and one of the major antithrombogenic agent widely used for the prevention of heart attacks and stroke.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Aspirin may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric techique and reversed-phase high-performance liquid chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC1066 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

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PHR1941

Aspirin Impurity E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1942

Aspirin Impurity F, Pharmaceutical Secondary Standard; Certified Reference Material

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Simultaneous determination of clopidogrel and aspirin in pharmaceutical dosage forms
Mishra P and Dolly A
Indian Journal of Pharmaceutical Sciences, 68(3) (2006)
Rapid and simultaneous determination of aspirin and dipyridamole in pharmaceutical formulations by reversed-phase high performance liquid chromatography (RP-HPLC) method
Prakash K, et al.
African Journal of Pharmacy and Pharmacology, 5(2), 244-251 (2011)

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