PHR1909
Atenolol
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
Atenolol, (±)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide, 4-[2′-Hydroxy-3′-(isopropylamino)propoxy]phenylacetamide
About This Item
grade
certified reference material
pharmaceutical secondary standard
Quality Level
Agency
traceable to BP 492
traceable to Ph. Eur. A1340000
traceable to USP 1044403
API family
atenolol
form
powder
CofA
current certificate can be downloaded
packaging
pkg of 500 mg
application(s)
pharmaceutical
storage temp.
2-30°C
SMILES string
CC(C)NCC(O)COc1ccc(CC(N)=O)cc1
InChI
1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)
InChI key
METKIMKYRPQLGS-UHFFFAOYSA-N
Gene Information
human ... ADRB1(153)
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General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Atenolol is a beta-1 blocker used in the treatment of various cardiovascular diseases.
Application
- Simultaneous analysis of atenolol and nifedipine using magnesium oxide-nanoplatelets (MgO-NPLs) modified screen-printed electrodes (SPEs) by differential pulse voltammetry (DPV) from pharmaceutical dosage forms and urine samples
- Voltammetric determination of amlodipine besylate and atenolol in their combined pharmaceutical formulations using a cathodically pretreated-boron doped diamond electrode (CP-BDDE)
- Spectrofluorimetric determination of atenolol using gold nanoparticles (AuNPs) based photo probes in commercial tablets
- Amperometric estimation of atenolol using bismuth vanadate-bismuth(III) oxide (BiVO4–Bi2O) composite electrode in pharmaceutical formulations and human urine samples
- Development of a reversed phase-high performance liquid chromatography (RP-HPLC) method coupled to a photodiode array detector (PDA) for the quantitative analysis of atenolol and trimetazidine in human urine and pharmaceutical tablets
Analysis Note
Footnote
Recommended products
related product
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Articles
TLC plates, with silica gel, gypsum as binder, International Pharmacopoeia compliant, for identification of Atenolol and Chlorthalidone in tablets.
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