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PHR1708

Supelco

Ascorbic acid Impurity C

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
D-xylo-Hex-2-ulosonic acid, D-sorbosonic acid
Empirical Formula (Hill Notation):
C6H10O7
CAS Number:
Molecular Weight:
194.14
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to Ph. Eur. Y0001024

API family

ascorbic acid

CofA

current certificate can be downloaded

packaging

pkg of 30 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ascorbic acid Impurity C is an impurity of ascorbic acid (AA), which is also known as vitamin C. It is found in plant tissues and exhibits antioxidant property.

Application

Ascorbic acid may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using automatic potentiometric flow titration method.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3015 in the slot below. This is an example certificate only and may not be the lot that you receive.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Automatic potentiometric flow titration procedure for ascorbic acid determination in pharmaceutical formulations
Paim SPA, et al.
Journal of Pharmaceutical and Biomedical Analysis, 28(6), 1221-1225 (2002)

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