Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

PHR1701

Supelco

Triamcinolone Acetonide

Pharmaceutical Secondary Standard; Certified Reference Material

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
Triamcinolone acetonide, 9α-Fluoro-11β,16α,17α,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-acetonide, 9α-Fluoro-16α-hydroxyprednisolone 16α,17α-acetonide
Empirical Formula (Hill Notation):
C24H31FO6
CAS Number:
76-25-5
Molecular Weight:
434.50
EC Number:
200-948-7
MDL number:
MFCD00056834
UNSPSC Code:
41116107
PubChem Substance ID:
329823564
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to Ph. Eur. T1900000
traceable to USP 1677002

API family

triamcinolone

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(C)(C)O[C@@]45C(=O)CO

InChI

1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1

InChI key

YNDXUCZADRHECN-JNQJZLCISA-N

Gene Information

human ... NR3C1(2908)

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Triamcinolone Acetonide is a glucocorticoid and a derivative of pregnane, used mainly in the treatment of rheumatic disease, allergic and dermatologic symptoms.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Triamcinolone Acetonide may be used as a pharmaceutical standard for the determination of the analyte in drug dosage forms by high performance liquid chromatography and spectrophotometry.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2813 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H302,H360

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Determination of methylparaben, propylparaben, triamcinolone acetonide and its degradation product in a topical cream by RP-HPLC.
Matysova L, et al.
Analytical and Bioanalytical Chemistry, 376(4), 440-443 (2003)
Simultaneous determination of terbinafine HCL and triamcinolone acetonide by UV derivative spectrophotometry and spectrodensitometry.
El-Saharty YS, et al.
Journal of Pharmaceutical and Biomedical Analysis, 28(3-4), 569-580 (2002)
Triamcinolone acetonide.
Jeal W and Faulds D
Drugs, 53(2), 257-280 (1997)
Simultaneous determination of triamcinolone acetonide and oxymetazoline hydrochloride in nasal spray formulations by HPLC.
Sudsakorn S, et al.
Journal of Pharmaceutical and Biomedical Analysis, 40(5), 1273-1280 (2006)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service