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PHR1699

Supelco

Lutein

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Xanthophyll, α-Carotene-3,3′-diol, β, ε-carotene, β, ε-carotene-3,3′-diol, Lutein

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About This Item

Empirical Formula (Hill Notation):
C40H56O2
CAS Number:
127-40-2
Molecular Weight:
568.87
Beilstein:
2068547
EC Number:
204-840-0
MDL number:
MFCD08435941
UNSPSC Code:
41116107
PubChem Substance ID:
329823562
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to USP 1370804

API family

lutein

CofA

current certificate can be downloaded

packaging

pkg of 3x100 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

-10 to -25°C

SMILES string

CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)C[C@@H](O)CC1(C)C)\C=C\C=C(C)\C=C\[C@H]2C(C)=C[C@H](O)CC2(C)C

InChI

1S/C40H56O2/c1-29(17-13-19-31(3)21-23-37-33(5)25-35(41)27-39(37,7)8)15-11-12-16-30(2)18-14-20-32(4)22-24-38-34(6)26-36(42)28-40(38,9)10/h11-25,35-37,41-42H,26-28H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,29-15+,30-16+,31-19+,32-20+/t35-,36+,37-/m0/s1

InChI key

KBPHJBAIARWVSC-RGZFRNHPSA-N

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General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Lutein is an oxygenated derivative of hydrocarbon carotenoids present in dark green and leafy vegetables. It acts as a lipophilic drug (logP 7.8) which is majorly utilized for the prevention of age-related macular degeneration (AMD), cataracts, and other blinding disorders.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Dietary carotenoid with no vitamin A potency. Increases macular pigment concentration in the eye and may improve visual function.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB3708 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

related product

Product No.
Description
Pricing

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAD7725
LRAD5328
LRAC6944
LRAB3708
LRAA6965

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Solid self-nanoemulsifying drug delivery system (S-SNEDDS) containing phosphatidylcholine for enhanced bioavailability of highly lipophilic bioactive carotenoid lutein
Shanmugam S, et al.
European Journal of Pharmaceutics and Biopharmaceutics, 79(2), 250-257 (2011)
Maria V Chandra-Hioe et al.
Plant foods for human nutrition (Dordrecht, Netherlands), 74(1), 34-39 (2018-10-12)
Lutein is a xanthophyll, a bioactive phytochemical that presents itself as colourful pigments in plants. Australian sweet lupin flour has been incorporated as a food ingredient in wheat bread and pasta to improve their sensory property and nutritional quality. However, the

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