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PHR1567

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Gibberellic Acid

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Gibberellic acid, GA3, Gibberellin A3

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About This Item

Empirical Formula (Hill Notation):
C19H22O6
CAS Number:
77-06-5
Molecular Weight:
346.37
Beilstein:
54346
EC Number:
201-001-0
MDL number:
MFCD00079329
UNSPSC Code:
41116107
PubChem Substance ID:
329823476
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to USP 1291005

API family

gibberellic acid

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

C[C@]12[C@@H](O)C=C[C@@]3(OC1=O)[C@@H]4CC[C@]5(O)C[C@]4(CC5=C)[C@H]([C@H]23)C(O)=O

InChI

1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10-,11+,12-,13-,16-,17+,18+,19-/m1/s1

InChI key

IXORZMNAPKEEDV-OBDJNFEBSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Gibberellic Acid is produced because of the metabolism of Gibberella fujikuroi (imperfect stage, Fusarium moniliforme). It is known as a growth substance for plants. Owing to its influence on growth rate as well as morphology of plants, and flower induction, gibberellic acid has been extensively synthesized by chemical and pharmaceutical industries.
Gibberellic acid is an endogenous plant growth regulator

Application

Gibberellic Acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC) and fluorometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Phytohormone that controls important aspects of plant growth: germination, elongation, and flowering. The effects are mediated by inducing degradation of the DELLA repressor protein, and probably other minor signalling pathways.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA4483 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

农药列管产品

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAD3856
LRAC4957
LRAA4483

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Fluorometric determination of gibberellic and gibberellenic acids in fermentation products, commercial formulations, and purified materials
Kavanagh F and Kuzel NR
Journal of Agricultural and Food Chemistry, 6(6), 459-463 (1958)
In vitro production and efficient quantification of major phytopharmaceuticals in an endangered medicinal herb, Swertia chirata
Kumar V, et al.
International Journal of Biotechnology and Bioengineering Research, 4, 495-506 (2013)

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