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PHR1519

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Sulfacetamide Sodium

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Sulfacetamide sodium salt monohydrate

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About This Item

Empirical Formula (Hill Notation):
C8H9N2NaO3S · H2O
CAS Number:
6209-17-2
Molecular Weight:
254.24
MDL number:
MFCD00149555
UNSPSC Code:
41116107
PubChem Substance ID:
329823434
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to Ph. Eur. S1700000
traceable to USP 1624006

API family

sulfacetamide

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

NC1=CC=C(S(N([Na])C(C)=O)(=O)=O)C=C1.O

InChI

1S/C8H10N2O3S.Na.H2O/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8;;/h2-5H,9H2,1H3,(H,10,11);;1H2/q;+1;/p-1

InChI key

IHCDKJZZFOUARO-UHFFFAOYSA-M

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General description

Sulfacetamide Sodium belongs to the class of sulfonamides, widely used in ophthalmic preparations, to treat different ocular infections such as corneal ulcers and conjunctivitis. It shows bactericidal activity against susceptible microorganisms.

Application

Sulfacetamide Sodium may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations by spectrometric technique and micellar electro-kinetic chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA3326 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAD3509
LRAC4565
LRAC2790
LRAA3326

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Determination of prednisolone acetate, sulfacetamide and phenylefrine in local pharmaceutical preparations by micellar electrokinetic chromatography
Gallego LMJ and Arroyo PJ
Journal of Pharmaceutical and Biomedical Analysis, 31(5), 873-884 (2003)
Pharmacology, 9(2), 126-126 (2014)
Validation of a stability-indicating spectrometric method for the determination of sulfacetamide sodium in pure form and ophthalmic preparations
Ahmed S, et al.
Journal of Pharmacy & Bioallied Sciences, 9(2), 126-126 (2017)

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