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PHR1518

Polydimethylsiloxane

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Dimethylpolysiloxane, Polydimethylsiloxane

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About This Item

CAS Number:
9016-00-6
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
MFCD00084411

Key Documents

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Product Name

Polydimethylsiloxane, Pharmaceutical Secondary Standard; Certified Reference Material

SMILES string

[Si](=O)(C)C

InChI

1S/C2H6OSi/c1-4(2)3/h1-2H3

InChI key

SEUDSDUUJXTXSV-UHFFFAOYSA-N

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. S0600000
traceable to USP 1546300

API family

polydimethylsiloxane

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

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Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

Clear, colorless fluid polymer useful as a stationary phase in gas chromatography and as an anti-foaming agent.
It was used in a study performed to understand its molecular weight and molecular weight distribution by off-line coupling of GPC with MALDI mass spectrometer.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Poly(dimethylsiloxane) [PDMS] is a polymer. It is a stable silicone rubber. It has been used as ion selective membrane for ion-sensitive field-effect transistors, as spring material in accelerometers, elastomer on a tactile sensor and as flexible encapsulation material in decouple sensors.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB7823 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

609.8 °F - closed cup

flash_point_c

321 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Robust and biodegradable elastomers based on corn starch and polydimethylsiloxane (PDMS).
Ceseracciu L
ACS Applied Materials & Interfaces, 7(6), 3742-3753 (2015)
Molecular weight distribution of poly (dimethylsiloxane) by combining matrix-assisted laser desorption/ionization time-of-flight mass spectrometry with gel-permeation chromatography fractionation.
Montaudo, Giorgio, et al.
Rapid Communications in Mass Spectrometry, 9.12, 1158-1163 (1995)

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