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PHR1490

Monoethanolamine

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Ethanolamine, 2-Aminoethanol, 2-Aminoethyl alcohol, ETA, MEA, MEA 90, MEA-LCI, Monoethanolamine

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About This Item

Linear Formula:
NH2CH2CH2OH
CAS Number:
141-43-5
Molecular Weight:
61.08
EC Number:
205-483-3
UNSPSC Code:
41116107
NACRES:
NA.24
Beilstein/REAXYS Number:
505944
MDL number:
MFCD00008183

Key Documents

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Product Name

Monoethanolamine, Pharmaceutical Secondary Standard; Certified Reference Material

InChI

1S/C2H7NO/c3-1-2-4/h4H,1-3H2

InChI key

HZAXFHJVJLSVMW-UHFFFAOYSA-N

SMILES string

NCCO

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. Y0001184
traceable to USP 1445925

vapor density

2.1 (vs air)

vapor pressure

0.2 mmHg ( 20 °C)

description

Pharmaceutical Secondary Standard; Certified Reference Material

API family

ethanolamine

CofA

current certificate can be downloaded

autoignition temp.

1436 °F

expl. lim.

17 %

packaging

pkg of 1 mL

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.454 (lit.)

bp

170 °C (lit.)
69-70 °C/10 mmHg

mp

10-11 °C (lit.)

density

1.012 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

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Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

Monoethanolamine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations and cosmetic products by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Monoethanolamine is majorly used in pharmaceutical formulations in the buffer systems, and emulsion preparations. It can also be used as a solvent for fats and oils and to synthesize many salts having therapeutic essence.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC2076 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

195.8 °F - Pensky-Martens closed cup

flash_point_c

91 °C - Pensky-Martens closed cup

Regulatory Information

危险化学品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Simultaneous analysis of mono-, di-, and tri-ethanolamine in cosmetic products using liquid chromatography coupled tandem mass spectrometry
Shin KO and Lee YM
Archives of Pharmacal Research, 39(1), 66-72 (2016)
Handbook of Pharmaceutical Excipients (2009)
Monoethanolamine
USP42-NF37
United States Pharmacopeia/National Formulary, 31(5), 5836-5836 (2013)

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