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PHR1483

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Ferrous Sulfate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Iron(II) sulfate heptahydrate, Ferrous sulfate heptahydrate

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About This Item

Linear Formula:
FeSO4 · 7H2O
CAS Number:
7782-63-0
Molecular Weight:
278.01
MDL number:
MFCD00149719
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to USP 1270355

vapor pressure

14.6 mmHg ( 25 °C)

API family

ferrous sulfate

CofA

current certificate can be downloaded

packaging

pkg of 1 g

density

1.898 g/mL at 25 °C (lit.)

application(s)

pharmaceutical

format

neat

storage temp.

2-8°C

SMILES string

O.O.O.O.O.O.O.[Fe++].[O-]S([O-])(=O)=O

InChI

1S/Fe.H2O4S.7H2O/c;1-5(2,3)4;;;;;;;/h;(H2,1,2,3,4);7*1H2/q+2;;;;;;;;/p-2

InChI key

SURQXAFEQWPFPV-UHFFFAOYSA-L

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General description

Ferrous sulfate is the sulfate salt of divalent cation form of iron. It is an essential body mineral, that is commonly used in the treatment of iron deficiency anemia.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Ferrous sulfate may be used as a reference standard for the determination of the analyte in bulk drug and pharmaceutical formulation by titrimetry and spectroscopy.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA3031 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

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Product No.
Description
Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAD5396
LRAC7148
LRAA3031

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Determination of the iron state in ferrous iron containing vitamins and dietary supplements: application of Mossbauer spectroscopy
Oshtrakh MI, et al.
Journal of Pharmaceutical and Biomedical Analysis, 40(5), 1281-1287 (2006)
Thomas Delompré et al.
Foods (Basel, Switzerland), 9(10) (2020-10-18)
Orally Disintegrating Tablets (ODTs) are used to restore the nutritional status of people suffering from swallowing pathologies such as dysphagia. ODTs are consumed without water intake and are easily swallowed. The main active compounds of ODTs are vitamins and minerals.
Ferrous sulfate
USP43/NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 40(5)(19), 1862-1862 (2015)
Iron-deficiency anemia
Camaschella C
The New England Journal of Medicine, 372(19), 1832-1843 (2015)

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