Skip to Content
Merck
CN

PHR1473

o-Toluenesulfonamide

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

o-Toluenesulfonamide

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
CH3C6H4SO2NH2
CAS Number:
88-19-7
Molecular Weight:
171.22
NACRES:
NA.24
PubChem Substance ID:
329823402
UNSPSC Code:
41116107
EC Number:
201-808-8
MDL number:
MFCD00007934

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

o-Toluenesulfonamide, Pharmaceutical Secondary Standard; Certified Reference Material

InChI

1S/C7H9NO2S/c1-6-4-2-3-5-7(6)11(8,9)10/h2-5H,1H3,(H2,8,9,10)

InChI key

YCMLQMDWSXFTIF-UHFFFAOYSA-N

SMILES string

Cc1ccccc1S(N)(=O)=O

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1672010

API family

saccharin

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

156-158 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

Looking for similar products? Visit Product Comparison Guide

Related Categories

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA3021 in the slot below. This is an example certificate only and may not be the lot that you receive.
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

o-Toluenesulfonamide has been used as a pharmaceutical secondary standard for the determination of the analyte in pharmaceutical packaging systems using gas chromatography-flame ionization detection (GC-FID) and gas chromatography-mass spectrometry (GC-MS).
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. o-Toluenesulfonamide is a major impurity in artificial sweetening substances containing saccharin.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

hcodes

H319,H351

Hazard Classifications

Carc. 2 - Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Utilization of internal standard response factors to estimate the concentration of organic compounds leached from pharmaceutical packaging systems and application of such estimated concentrations to safety assessment
Jenke D and Odufu A
Journal of Chromatographic Science, 50(3), 206-212 (2012)

Related Content

最新推出的满足海关审查要求的标准物质

默克Supelco®标准物质不断推出或更新满足海关及法规要求的标准物质。每年我们约有上百种的新CRM或标准物质上市，在此我们尽可能多的列出满足海关及法规要求的标准物质。

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service