PHR1469
Hydroquinone
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
Hydroquinone, 1,4-Benzenediol, 1,4-Dihydroxybenzene, HQ
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About This Item
Linear Formula:
C6H4-1,4-(OH)2
CAS Number:
Molecular Weight:
110.11
Beilstein:
605970
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
grade
certified reference material
pharmaceutical secondary standard
Quality Level
Agency
traceable to USP 1324002
vapor density
3.81 (vs air)
vapor pressure
1 mmHg ( 132 °C)
API family
hydroquinone
CofA
current certificate can be downloaded
autoignition temp.
930 °F
packaging
pkg of 1 g
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
bp
285 °C (lit.)
mp
172-175 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
SMILES string
Oc1ccc(O)cc1
InChI
1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H
InChI key
QIGBRXMKCJKVMJ-UHFFFAOYSA-N
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General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
Hydroquinone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC) and spectrophotometry techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAA3017 in the slot below. This is an example certificate only and may not be the lot that you receive.
Recommended products
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
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Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1B
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
危险化学品
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Development and validation of a new RP-HPLC method for the simultaneous determination of hydroquinone, kojic acid, octinoxate, avobenzone, BHA and BHT in skin-whitening cream.
Galimany-Rovira F, et al.
Analytical Methods : Advancing Methods and Applications, 8(5), 1170-1180 (2016)
Automated flow-injection spectrophotometric determination of catecholamines (epinephrine and isoproterenol) in pharmaceutical formulations based on ferrous complex formation.
Solich P, et al.
Journal of Pharmaceutical and Biomedical Analysis, 22(5), 781-789 (2000)
Thomas Kruse et al.
Journal of bacteriology, 197(5), 893-904 (2014-12-17)
Desulfitobacterium dehalogenans is able to grow by organohalide respiration using 3-chloro-4-hydroxyphenyl acetate (Cl-OHPA) as an electron acceptor. We used a combination of genome sequencing, biochemical analysis of redox active components, and shotgun proteomics to study elements of the organohalide respiratory
Changming Chen et al.
Plant physiology, 166(1), 370-383 (2014-07-23)
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