Skip to Content

Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

For important updates on recent policy changes, please click here for more details.

Merck
CN
All Photos(1)

Key Documents

View All Documentation

PHR1454

Supelco

Arginine Hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

L-Arginine monohydrochloride, (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride, (S)-(+)-Arginine hydrochloride

Sign Into View Organizational & Contract Pricing

Select a Size

50 ML
CN¥1,251.31
250 ML
CN¥3,005.35

CN¥1,251.31

Available to ship onApril 23, 2025Details

Request a Bulk Order
All Photos(1)

Select a Size

Change View
50 ML
CN¥1,251.31
250 ML
CN¥3,005.35

About This Item

Empirical Formula (Hill Notation):
C6H14N4O2 · HCl
CAS Number:
1119-34-2
Molecular Weight:
210.66
Beilstein:
3631658
EC Number:
214-275-1
MDL number:
MFCD00064550
UNSPSC Code:
41116107
PubChem Substance ID:
329822614
NACRES:
NA.24

CN¥1,251.31

Available to ship onApril 23, 2025Details

Request a Bulk Order

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to BP 694
traceable to Ph. Eur. A1271000
traceable to USP 1042601

API family

arginine

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

236-230 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Arginine Hydrochloride is a salt of arginine, which is a semi-essential amino acid. This dibasic amino acid acts as a precursor for creatinine and is a natural constituent of most of the dietary proteins.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Arginine Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations, dietary supplements and capsules by chromatography.[1][2]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA3002 in the slot below. This is an example certificate only and may not be the lot that you receive.

related product

Product No.
Description
Pricing

PHR1106

L-Arginine, Pharmaceutical Secondary Standard; Certified Reference Material

A1271000

Arginine hydrochloride, European Pharmacopoeia (EP) Reference Standard

A1270000

Arginine, European Pharmacopoeia (EP) Reference Standard

Y0000304

Arginine aspartate, European Pharmacopoeia (EP) Reference Standard

1042500

L-Arginine, United States Pharmacopeia (USP) Reference Standard

1042554

Arginine ethyl ester dihydrochloride, United States Pharmacopeia (USP) Reference Standard

1042601

Arginine hydrochloride, United States Pharmacopeia (USP) Reference Standard

BP694

Arginine hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR2813

Arginine aspartate, certified reference material, pharmaceutical secondary standard

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number

    It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

    If you need assistance, please contact Customer Support.

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Quantification of arginine in dietary supplement tablets and capsules by silica gel high-performance thin-layer chromatography with visible mode densitometry
    Hess B and Sherma J
    Acta Chromatographica , 60-69 (2004)
    Arginine Hydrochloride
    USP42-NF37: United States Pharmacopeia and National Formulary
    United States Pharmacopeia/National Formulary, 44(5), 366-366 (2018)
    Nivaldo Ribeiro Villela et al.
    Journal of translational medicine, 12, 232-232 (2014-08-26)
    Relative hypovolemia is frequently found in early stages of severe sepsis and septic shock and prompt and aggressive fluid therapy has become standard of care improving tissue perfusion and patient outcome. This paper investigates the role of the nitric oxide
    Jenna Gallie et al.
    PLoS biology, 13(3), e1002109-e1002109 (2015-03-13)
    Phenotype switching is commonly observed in nature. This prevalence has allowed the elucidation of a number of underlying molecular mechanisms. However, little is known about how phenotypic switches arise and function in their early evolutionary stages. The first opportunity to
    X Zheng et al.
    Journal of dental research, 94(2), 344-353 (2014-12-06)
    Dental caries is closely associated with the microbial disequilibrium between acidogenic/aciduric pathogens and alkali-generating commensal residents within the dental plaque. Fluoride is a widely used anticaries agent, which promotes tooth hard-tissue remineralization and suppresses bacterial activities. Recent clinical trials have
    View All Related Papers

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service