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CN

PHR1407

Pamoic Acid

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Pamoic acid, 1,1′-Methylene-bis(2-hydroxy-3-naphthoic acid), 4,4′-Methylenebis(3-hydroxy-2-naphthoic acid), Embonic acid

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About This Item

Empirical Formula (Hill Notation):
C23H16O6
CAS Number:
130-85-8
Molecular Weight:
388.37
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823379
EC Number:
204-998-0
Beilstein/REAXYS Number:
901319
MDL number:
MFCD00004079

Key Documents

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Product Name

Pamoic Acid, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

WLJNZVDCPSBLRP-UHFFFAOYSA-N

InChI

1S/C23H16O6/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29/h1-10,24-25H,11H2,(H,26,27)(H,28,29)

SMILES string

OC(=O)c1cc2ccccc2c(Cc3c(O)c(cc4ccccc34)C(O)=O)c1O

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1493000

API family

oxantel, cycloguanil

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

≥300 °C (dec.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

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Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

Pamoic Acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA2471 in the slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Development and validation of a RP-HPLC method for quality control of oxantel pamoate, pyrantel pamoat and praziquantel in tablets
Tatar E, et al.
Marmara Pharmaceutical Journal, 19(1), 27-35 (2015)
Simultaneous determination of mebendazole and pyrantel pamoate from tablets by high performance liquid chromatography-reverse phase (RP-HPLC)
Argekar AP, et al.
Talanta, 44(11), 1959-1965 (1997)
Sara Montminy Paquette et al.
Pharmaceutical research, 31(8), 2065-2077 (2014-02-22)
Long-acting injectables (LAIs) are increasingly recognized as an effective therapeutic approach for treating chronic conditions. Many LAIs are formulated to create a poorly soluble depot from which the active agent is delivered over time. This long residing depot can cause

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