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PHR1395

Methocarbamol

Name: Methocarbamol
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Guaiacol glyceryl ether carbamate, Methocarbamol

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About This Item

Empirical Formula (Hill Notation):

C₁₁H₁₅NO₅

CAS Number:

532-03-6

Molecular Weight:

241.24

EC Number:

208-524-3

MDL number:

MFCD00057662

UNSPSC Code:

41116107

PubChem Substance ID:

329823369

NACRES:

NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to USP 1412008

API family

methocarbamol

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

NC(OCC(O)COC1=C(OC)C=CC=C1)=O

InChI

1S/C11H15NO5/c1-15-9-4-2-3-5-10(9)16-6-8(13)7-17-11(12)14/h2-5,8,13H,6-7H2,1H3,(H2,12,14)

InChI key

GNXFOGHNGIVQEH-UHFFFAOYSA-N

Gene Information

human ... CA1(759)

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Related Categories

Analytical Reference Standards

Certified Reference Materials

Pharmacopeia & Metrological Institute Standards

General description

Methocarbamol is drug, which is widely used as a skeletal muscle relaxant. It is also used in the treatment of musculoskeletal conditions, generally associated with painful muscle spasms, cramps, and dislocations.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Methocarbamol may be used as a secondary pharma standard for the quantification of the analyte in pharmaceutical formulations using liquid chromatography technique and spectrophotometric technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC4792 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

related product

Product No.

Description

Pricing

1412008

Methocarbamol, United States Pharmacopeia (USP) Reference Standard

Pictograms

GHS08,GHS07

Signal Word

Danger

Hazard Statements

H302,H317,H334

Precautionary Statements

P280 - P301 + P312 + P330 - P302 + P352

Hazard Classifications

Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Determination of methocarbamol in equine serum and urine by high-performance liquid chromatography with ultraviolet detection and atmospheric pressure ionization-mass spectrometric confirmation

Koupai-Abyazani RM, et al.

Journal of Analytical Toxicology, 21(4), 301-305 (1997)

Validation of a RP-LC method for simultaneous determination of paracetamol, methocarbamol and diclofenac potassium in tablets

Subramanian G, et al.

Indian Journal of Pharmaceutical Sciences, 67(2), 260-260 (2005)

Simultaneous determination of paracetamol and methocarbamol in tablets by ratio spectra derivative spectrophotometry and LC.

N Erk et al.

Journal of pharmaceutical and biomedical analysis, 24(3), 469-475 (2001-02-24)

The application of the ratio spectra derivative spectrophotometry and high-performance liquid chromatography (HPLC) to the simultaneous determination of paracetamol (PAR) and methocarbamol (MET) in combined pharmaceutical tablets is presented. The spectrophotometric procedure is based on the use of the first

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