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Key Documents

PHR1394

Supelco

Fluoxetine Hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Fluoxetine hydrochloride, FLX, (±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride, LY-110,140 hydrochloride, Prozac®

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100 TESTS
CN¥13,220.39

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100 TESTS
CN¥13,220.39

About This Item

Empirical Formula (Hill Notation):
C17H18F3NO · HCl
CAS Number:
Molecular Weight:
345.79
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

CN¥13,220.39


Estimated to ship onAugust 05, 2025Details


Request a Bulk Order

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to BP 797
traceable to Ph. Eur. F0253000
traceable to USP 1279804

API family

fluoxetine

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CNCCC(C1=CC=CC=C1)OC2=CC=C(C(F)(F)F)C=C2.[H]Cl

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71017BC71005BC71015BC
manufacturer/tradename

Assurance GDS®, BioControl Systems 71018-100

manufacturer/tradename

Assurance GDS®, BioControl Systems 71017-100

manufacturer/tradename

Assurance GDS®, BioControl Systems 71005-100

manufacturer/tradename

Assurance GDS®, BioControl Systems 71015-100, BioControl Systems 71015-576

suitability

enterovirulent E. coli (EEC) (shiga toxigenic)

suitability

enterovirulent E. coli (EEC) (shiga toxigenic)

suitability

Escherichia coli (O157:H7)

suitability

enterovirulent E. coli (EEC) (shiga toxigenic)

compatibility

for use with GDS Rotor-Gene

compatibility

for use with GDS Rotor-Gene

compatibility

for use with GDS Rotor-Gene

compatibility

for use with GDS Rotor-Gene

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

technique(s)

PCR: suitable

technique(s)

PCR: suitable

technique(s)

PCR: suitable

technique(s)

PCR: suitable

application(s)

food and beverages
pathogen testing

application(s)

food and beverages
pathogen testing

application(s)

food and beverages
pathogen testing

application(s)

food and beverages
pathogen testing

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Fluoxetine Hydrochloride is a selective serotonin-reuptake inhibitor used as an antidepressant. It is also utilized for the treatment of obsessive-compulsive disorders.[1]

Application

Fluoxetine Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography[2][3][4] techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Selective serotonin reuptake inhibitor; antidepressant.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3045 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

Sold under license from Eli Lilly and Company.
Prozac is a registered trademark of Eli Lilly and Co.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - STOT RE 2 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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    Simultaneous RP-HPLC and HPTLC Estimation of Fluoxetine Hydrochloride and Olanzapine in Tablet Dosage Forms
    Patel S and Patel NJ
    Indian Journal of Pharmaceutical Sciences, 71(4), 477-477 (2009)
    Quality assessment of internet pharmaceutical products using traditional and non-traditional analytical techniques
    Westenberger BJ, et al.
    International Journal of Pharmaceutics, 306(1), 56-70 (2005)
    Francisco Javier Maza et al.
    The Journal of experimental biology, 226(8) (2023-03-21)
    The interactions between memory processes and emotions are complex. Our previous investigations in the crab Neohelice led to an adaptation of the affective extension of sometimes opponent processes (AESOP) model. The model proposes that emotions generate separate emotive memory traces
    Determination of fluoxetine hydrochloride enantiomeric excess using high-performance liquid chromatography with chiral stationary phases
    Olsen BA, et al.
    Journal of Pharmaceutical and Biomedical Analysis, 17(4), 623-630 (1998)
    Min-Kyung Joo et al.
    Scientific reports, 13(1), 15529-15529 (2023-09-20)
    Antibiotics are increasingly recognized as causing neuropsychiatric side effects including depression and anxiety. Alterations in central serotonin and 5-HT receptor expression are implicated in the pathogenesis of anxiety and depression, which are highly comorbid with gastrointestinal disorders. Nevertheless, it is

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