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PHR1368

Supelco

Lamotrigine Related Compound B

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
2,3-Dichlorobenzoic acid
Linear Formula:
Cl2C6H3CO2H
CAS Number:
50-45-3
Molecular Weight:
191.01
Beilstein:
1946217
EC Number:
200-039-5
MDL number:
MFCD00002413
UNSPSC Code:
41116107
PubChem Substance ID:
329823347
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

100

Agency

traceable to Ph. Eur. Y0001032
traceable to USP 1356778

API family

lamotrigine

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

168-170 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

OC(=O)c1cccc(Cl)c1Cl

InChI

1S/C7H4Cl2O2/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3H,(H,10,11)

InChI key

QAOJBHRZQQDFHA-UHFFFAOYSA-N

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General description

2,3-Dichlorobenzoic acid is the main impurity of lamotrigine. It is a chlorobenzoate compound.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA1472 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

related product

Product No.
Description
Pricing

Y0001085

Lamotrigine for system suitability, European Pharmacopoeia (EP) Reference Standard

Y0001031

Lamotrigine for peak identification, European Pharmacopoeia (EP) Reference Standard

Y0001030

Lamotrigine, European Pharmacopoeia (EP) Reference Standard

Y0001032

Lamotrigine impurity E, European Pharmacopoeia (EP) Reference Standard

1356778

Lamotrigine Related Compound B, United States Pharmacopeia (USP) Reference Standard

1356790

Lamotrigine Related Compound D, United States Pharmacopeia (USP) Reference Standard

1356789

Lamotrigine Related Compound C, United States Pharmacopeia (USP) Reference Standard

PHR1392

Lamotrigine, Pharmaceutical Secondary Standard; Certified Reference Material

BP1097

Lamotrigine, British Pharmacopoeia (BP) Reference Standard

BP1098

Lamotrigine impurity standard, British Pharmacopoeia (BP) Reference Standard

PHR8729

Lamotrigine Related Compound C, certified reference material, pharmaceutical secondary standard

PHR8730

Lamotrigine Related Compound D, certified reference material, pharmaceutical secondary standard

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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