PHR1326
Calcium carbonate
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
Calcium carbonate
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About This Item
Linear Formula:
CaCO3
CAS Number:
Molecular Weight:
100.09
Beilstein:
8008338
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
grade
certified reference material
pharmaceutical secondary standard
Quality Level
Agency
traceable to USP 1086403
API family
calcium carbonate
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
density
2.93 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
SMILES string
[Ca++].[O-]C([O-])=O
InChI
1S/CH2O3.Ca/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2
InChI key
VTYYLEPIZMXCLO-UHFFFAOYSA-L
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General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Calcium carbonate is a material that is widely found in nature, and is commonly referred to as calcite. Calcium carbonate is used in such processes as the manufacture of paper, paints, glass, and ceramics, the compounding of polymers, environmental applications such as wastewater treatment, and as an extender in paints and coatings.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAC3446 in the slot below. This is an example certificate only and may not be the lot that you receive.
related product
Product No.
Description
Pricing
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Calcium carbonate urolithiasis in an adult male cynomolgus monkey.
C M O'Rourke et al.
Laboratory animal science, 45(2), 222-224 (1995-04-01)
Dongni Ren et al.
Micron (Oxford, England : 1993), 42(3), 228-245 (2010-10-19)
The review focuses on the effects of several important additives and templates controlling the calcium carbonate crystals formation and the complexity of the crystal morphologies in vitro. Additives include soluble matrices extracted from shells and pearls, amino-acids, magnesium ions and
Liliana Astachov et al.
Frontiers in bioscience (Landmark edition), 16, 458-471 (2011-01-05)
Stem cell development and fate decisions are dictated by the microenvironment in which the stem cell is embedded. Among the advanced goals of tissue engineering is the creation of a microenvironment that will support the maintenance and differentiation of the
Julyan H E Cartwright et al.
Angewandte Chemie (International ed. in English), 51(48), 11960-11970 (2012-11-06)
Although the polymorphism of calcium carbonate is well known, and its polymorphs--calcite, aragonite, and vaterite--have been highly studied in the context of biomineralization, polyamorphism is a much more recently discovered phenomenon, and the existence of more than one amorphous phase
Polysaccharides and proteoglycans in calcium carbonate-based biomineralization.
José L Arias et al.
Chemical reviews, 108(11), 4475-4482 (2008-07-26)
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