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PHR1248

Supelco

Maltitol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

4-O-α-Glucopyranosyl-D-sorbitol

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About This Item

Empirical Formula (Hill Notation):
C12H24O11
CAS Number:
585-88-6
Molecular Weight:
344.31
Beilstein:
89983
EC Number:
209-567-0
MDL number:
MFCD00006600
UNSPSC Code:
41116107
PubChem Substance ID:
329823252
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to Ph. Eur. M0160000
traceable to USP 1374907

API family

maltitol

CofA

current certificate can be downloaded

analyte chemical class(es)

oligosaccharides

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

149-152 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

OC[C@H](O)[C@@H](O)[C@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)CO

InChI

1S/C12H24O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h4-21H,1-3H2/t4-,5+,6+,7+,8+,9-,10+,11+,12+/m0/s1

InChI key

VQHSOMBJVWLPSR-WUJBLJFYSA-N

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General description

Maltitol is a sugar alcohol and nutritive sweetener, exhibiting reduced laxative effects, hence finds applications in different food products, beverages and dietary supplements.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Sugar substitute with a weak genotoxic effect.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB7670 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

related product

Product No.
Description
Pricing

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

涉药品监管产品

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAD8540
LRAD4869
LRAC6476
P500248
LRAB7670

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Determination of maltitol, isomaltitol, and lactitol by high-pH anion-exchange chromatography with pulsed amperometric detection
Cataldi.I.RT, et al.
Journal of Agricultural and Food Chemistry, 47(1), 157-163 (1999)
Simultaneous separation and determination of erythritol, xylitol, sorbitol, mannitol, maltitol, fructose, glucose, sucrose and maltose in food products by high performance liquid chromatography coupled to charged aerosol detector
Grembecka M, et al.
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 117, 77-82 (2014)
Sergey Vyazovkin et al.
Pharmaceutical research, 23(9), 2158-2164 (2006-09-05)
To demonstrate the utility of differential scanning calorimetry (DSC) for determining activation energy landscape in amorphous pharmaceutical systems throughout the sub-Tg and Tg regions. DSC was employed to determine the effective activation energies (E) of the relaxation in sub-Tg and
Vasso Psimouli et al.
Journal of the science of food and agriculture, 92(1), 99-105 (2011-08-13)
The aim of this research was to investigate whether certain polyols (mannitol, maltitol, sorbitol, lactitol), fructose, oligofructose and polydextrose can replace sugar (by an equal amount of each substitute) in cake formulations. The rheological behaviour of the cake batter and
S Nakamura et al.
European journal of clinical nutrition, 61(9), 1086-1093 (2007-01-26)
To estimate the suppressive effect of partially hydrolyzed guar gum (PHGG) on transitory diarrhea induced by ingestion of a sufficient amount of maltitol or lactitol in female subjects. The first, the minimal dose level of maltitol and lactitol that would
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