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PHR1235

Supelco

Retinyl Palmitate (Vitamin A Palmitate)

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Retinyl palmitate, Vitamin A palmitate, all−trans−Retinol palmitate

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10 ML
¥1,255.98
50 ML
¥3,671.61

¥1,255.98

Available to ship on2025年4月16日Details

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10 ML
¥1,255.98
50 ML
¥3,671.61

About This Item

Empirical Formula (Hill Notation):
C36H60O2
CAS Number:
79-81-2
Molecular Weight:
524.86
Beilstein:
1917366
EC Number:
201-228-5
MDL number:
MFCD00019414
UNSPSC Code:
41116107
PubChem Substance ID:
329823240
NACRES:
NA.24

¥1,255.98

Available to ship on2025年4月16日Details

Request a Bulk Order

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to USP 1602502

API family

retinyl compounds

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(CCCCCCCCCCCCCCC)=O)C(C)(C)CCC1

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General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.Retinyl palmitate belongs to a category of compounds called retinoids, which are chemically similar to vitamin A. It exhibits a beneficial effect on vision, skin and immune function, inhibits cell proliferation and prevents cancer. It is an important dietary as well as a therapeutic compound.[1]

Application

Retinyl palmitate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatographic[2] and spectrophotometric[3] techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Review: Vitamin A metabolism.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC1694 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H360D,H412

Hazard Classifications

Aquatic Chronic 3 - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

No data available

Flash Point(C)

No data available

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    Vitamin A Palmitate-β-cyclodextrin inclusion complexes: Characterization, protection and emulsification properties
    Vilanova N and Solans C
    Food Chemistry, 175(1-2), 529 -5535 (2015)
    Development of a method for quantitation of retinol and retinyl palmitate in human serum using high-performance liquid chromatography -atmospheric pressure chemical ionization -mass spectrometry
    van Breemen RB, et al.
    Journal of Chromatography A, 794(1-2), 245-251 (1998)
    S Pedersen-Bjergaard et al.
    Journal of chromatography. A, 876(1-2), 201-211 (2000-05-24)
    Microemulsion electrokinetic chromatography (MEEKC) was carried out in a pH 2.5 phosphate buffer to effectively suppress the electroosmotic flow (EOF). With 66.6% (w/w) 25 mM phosphate buffer pH 2.5, 20.0% (w/w) 2-propanol, 6.6% (w/w) 1-butanol, 6.0% (w/w) sodium lauryl sulphate
    I J Martins et al.
    Biochimica et biophysica acta, 1081(3), 328-338 (1991-02-05)
    There are inverse relationships between HDL cholesterol and plasma triacylglycerol concentrations in normal and in hypertriglyceridemic individuals. To investigate the interactions between triacylglycerol-rich lipid particles and HDL, a lipid emulsion model of the triacylglycerol-rich lipoproteins was prepared. When emulsion particles
    Eliot L Berson et al.
    Archives of ophthalmology (Chicago, Ill. : 1960), 130(6), 707-711 (2012-02-15)
    To evaluate whether a diet high in long chain ω-3 fatty acids can slow the rate of visual acuity loss among patients with retinitis pigmentosa receiving vitamin A palmitate. We calculated dietary intake from questionnaires completed annually by 357 adult
    View All Related Papers

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