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PHR1215

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Lactic acid

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
DL-Lactic acid, 2-Hydroxypropionic acid
Linear Formula:
CH3CH(OH)COOH
CAS Number:
50-21-5
Molecular Weight:
90.08
Beilstein:
1209341
EC Number:
200-018-0
MDL number:
MFCD00004520
UNSPSC Code:
41116107
PubChem Substance ID:
329823222
E Number:
E270
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to USP 1356734

API family

lactic acid

form

liquid

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.425 (lit.)

bp

122 °C/15 mmHg (lit.)

density

1.209 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

storage temp.

2-8°C

SMILES string

CC(O)C(O)=O

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)

InChI key

JVTAAEKCZFNVCJ-UHFFFAOYSA-N

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General description

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

This pharmaceutical secondary standard can also be used as follows:

  • Quantitative analysis of four short-chain fatty acids and lactic acids by high-performance liquid chromatography (HPLC) combined with a UV detector from the supernatant of bacterial cultures
  • Spectrophotometric determination of lactic acid at 390 nm in biological cultural and dairy products

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC0299 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1C

Supplementary Hazards

EUH071

WGK

WGK 1

Flash Point(F)

235.4 °F

Flash Point(C)

113 °C

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Spectrophotometric determination of lactic acid
Borshchevskaya LN, et al.
Journal of Analytical Chemistry, 71, 755-758 (2016)
Oystein Sylta et al.
International journal of sports physiology and performance, 9(1), 100-107 (2014-01-11)
The authors directly compared 3 frequently used methods of heart-rate-based training-intensity-distribution (TID) quantification in a large sample of training sessions performed by elite endurance athletes. Twenty-nine elite cross-country skiers (16 male, 13 female; 25 ± 4 y; 70 ± 11
Annabelle Olsson et al.
Journal of wildlife diseases, 49(3), 560-567 (2013-06-20)
Using a prospective, randomized study design we demonstrate that midazolam sedation minimizes acidosis compared with physical restraint in captive juvenile estuarine crocodiles during handling or noninvasive procedures at preferred body temperature. A dose of midazolam (5.0 mg/kg) was administered intramuscularly
Stephen Yiu Chuen Choi et al.
The Journal of pathology, 230(4), 350-355 (2013-06-05)
The common preference of cancers for lactic acid-generating metabolic energy pathways has led to proposals that their reprogrammed metabolism confers growth advantages such as decreased susceptibility to hypoxic stress. Recent observations, however, suggest that it generates a novel way for
Mohamed Ali Abdel-Rahman et al.
Biotechnology advances, 31(6), 877-902 (2013-04-30)
Fermentative production of optically pure lactic acid has roused interest among researchers in recent years due to its high potential for applications in a wide range of fields. More specifically, the sharp increase in manufacturing of biodegradable polylactic acid (PLA)
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