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PHR1155

Supelco

Octyldodecanol

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
2-Octyl-1-dodecanol
Linear Formula:
CH3(CH2)9CH[(CH2)7CH3]CH2OH
CAS Number:
5333-42-6
Molecular Weight:
298.55
EC Number:
226-242-9
MDL number:
MFCD01310428
UNSPSC Code:
41116107
PubChem Substance ID:
329823173
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to Ph. Eur. O0101000
traceable to USP 1477808

API family

octyldodecanol

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.453 (lit.)

bp

234-238 °C/33 mmHg (lit.)

mp

−1-1 °C (lit.)

density

0.838 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CCCCCCCCCCC(CO)CCCCCCCC

InChI

1S/C20H42O/c1-3-5-7-9-11-12-14-16-18-20(19-21)17-15-13-10-8-6-4-2/h20-21H,3-19H2,1-2H3

InChI key

LEACJMVNYZDSKR-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Octyldodecanol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Values of analytes vary lot to lot.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA7139 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Solvent effect on photostability of butyl methoxy di benzoyl methane formulated in solution and emulsion
DURANGO S, et al.
International Journal of Pharmacy and Pharmaceutical Sciences, 7(9), 181-186 (2015)
R S Lanigan
International journal of toxicology, 20 Suppl 3, 51-59 (2002-01-05)
Octyldodecyl Stearoyl Stearate functions as an occlusive skin-conditioning agent and as a nonaqueous viscosity-increasing agent in many cosmetic formulations. Current concentrations of use are between 0.7% and 23%, although historically higher concentrations were used. The chemical is formed by a
Contact sensitivity to octyldodecanol and trometamol in an anti-itch cream.
M Singh et al.
Contact dermatitis, 56(5), 289-290 (2007-04-20)
Thomas Mensing et al.
AIHA journal : a journal for the science of occupational and environmental health and safety, 64(4), 461-466 (2003-08-12)
Cooling lubricants are used in the metal industry during drilling or turning. Vapors and aerosols of these lubricants are suspected to induce airway hyperresponsiveness (AHR) in exposed workers. In a previous study the authors demonstrated that water-soluble lubricants induce AHR
Selection of solubility parameters for characterization of pharmaceutical excipients
Adamska K, et al.
Journal of Chromatography A, 1171(1-2), 90-97 (2007)
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