PHR1153
Triethyl citrate
Pharmaceutical Secondary Standard; Certified Reference Material
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Synonym(s):
Ethyl citrate
Linear Formula:
HOC(COOC2H5)(CH2COOC2H5)2
CAS Number:
Molecular Weight:
276.28
Beilstein:
1801199
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
certified reference material
pharmaceutical secondary standard
Quality Level
Agency
traceable to USP 1683606
vapor density
9.7 (vs air)
vapor pressure
1 mmHg ( 107 °C)
API family
triethyl citrate
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
refractive index
n20/D 1.442 (lit.)
bp
235 °C/150 mmHg (lit.)
density
1.14 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
SMILES string
CCOC(=O)CC(O)(CC(=O)OCC)C(=O)OCC
InChI
1S/C12H20O7/c1-4-17-9(13)7-12(16,11(15)19-6-3)8-10(14)18-5-2/h16H,4-8H2,1-3H3
InChI key
DOOTYTYQINUNNV-UHFFFAOYSA-N
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General description
Triethyl citrate is an ester of citric acid and is commonly used as a plasticizer in pharmaceutical coatings including tablets, capsules, beads and granules for masking taste. It is also used as a flavoring agent in food.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Triethyl citrate can be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Values of analytes vary lot to lot.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAA8988 in the slot below. This is an example certificate only and may not be the lot that you receive.
Recommended products
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
WGK
WGK 1
Flash Point(F)
311.0 °F
Flash Point(C)
155 °C
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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