Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

PHR1047

Supelco

Phenol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Hydroxybenzene

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
C6H5OH
CAS Number:
108-95-2
Molecular Weight:
94.11
Beilstein:
969616
EC Number:
203-632-7
MDL number:
MFCD00002143
UNSPSC Code:
41116107
PubChem Substance ID:
329823077
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to USP 1524806

vapor density

3.24 (vs air)

vapor pressure

0.09 psi ( 55 °C)
0.36 mmHg ( 20 °C)

API family

hexylresorcinol, guaiacol, salicylic acid

CofA

current certificate can be downloaded

autoignition temp.

1319 °F

expl. lim.

8.6 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

182 °C (lit.)

mp

40-42 °C (lit.)

density

1.071 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Oc1ccccc1

InChI

1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H

InChI key

ISWSIDIOOBJBQZ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Phenol is a derivative of benzene and is majorly used in the manufacture of bisphenol A, phenolic resins and caprolactam. Its other applications include the manufacture of variety of compounds in pharma industry, dyes, explosives, rubber and agriculture.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Phenol may be used as a standard in determining the concentration of phenol present in samples of water using gas chromatography coupled with electron capture detector (GC-ECD).
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC1665 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

related product

Product No.
Description
Pricing

PHR1013

Salicylic acid, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1136

Guaiacol, Pharmaceutical Secondary Standard; Certified Reference Material

1609002

Salicylic acid, United States Pharmacopeia (USP) Reference Standard

1551004

Potassium guaiacolsulfonate, United States Pharmacopeia (USP) Reference Standard

S0200000

Salicylic acid, European Pharmacopoeia (EP) Reference Standard

Y0000405

Salicylic acid impurity B, European Pharmacopoeia (EP) Reference Standard

H0420000

Hexylresorcinol, European Pharmacopoeia (EP) Reference Standard

Y0000619

Guaiacol, European Pharmacopoeia (EP) Reference Standard

1308307

Hexylresorcinol, United States Pharmacopeia (USP) Reference Standard

1524806

Phenol, United States Pharmacopeia (USP) Reference Standard

1609013

Salicylic acid Related Compound A, United States Pharmacopeia (USP) Reference Standard

1609024

Salicylic acid Related Compound B, United States Pharmacopeia (USP) Reference Standard

PHR1643

Salicylic Acid Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

1300004

Guaiacol, United States Pharmacopeia (USP) Reference Standard

Y0001746

Hexylresorcinol for system suitability, European Pharmacopoeia (EP) Reference Standard

BP775

Salicylic acid, British Pharmacopoeia (BP) Reference Standard

901604

Phenol solution, 1 M in dichloromethane

PHR2469

Guaiacol Impurity C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2472

Guaiacol Impurity H, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2473

Guaiacol Impurity G, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2475

Guaiacol Impurity E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR9076

2,5-Dimethoxyphenol, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR2474

Guaiacol Impurity A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2471

Guaiacol Impurity F, Pharmaceutical Secondary Standard; Certified Reference Material

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - STOT RE 2

Target Organs

Nervous system,Kidney,Liver,Skin

WGK

WGK 2

Regulatory Information

危险化学品

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAD7340
LRAD4792
LRAD1890
LRAC1665
LRAC1665

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Determination of trace amounts of phenol in river waters by gas chromatography
Rennie.JP
Analyst, 107, 327-330 (1982)
Encyclopaedia of Occupational Health and Safety: Industries and Occupations, 4 (1998)
Britta T Eklund et al.
Marine pollution bulletin, 46(2), 171-181 (2003-02-15)
Toxic effects on macroalgae have been compiled. Eighty-two articles have been found in literature during 1959-2000. A total of 120 substances were investigated using 65 different macroalgae species. About one-third of the tested compounds were organic substances (33%), another third
Kyoko Matsumoto et al.
Nucleic acids research, 42(16), e125-e125 (2014-07-19)
To identify and characterize transcript structures ranging from transcriptional start sites (TSSs) to poly(A)-addition sites (PASs), we constructed and analyzed human TSS/PAS mate pair full-length cDNA libraries from 14 tissue types and four cell lines. The collected information enabled us
Masaharu Nakamura et al.
Bioorganic & medicinal chemistry, 21(7), 1643-1651 (2013-03-07)
We previously reported that bis-phenol derivatives, including LG190178 (3a), possess not only vitamin D receptor (VDR) agonistic activity, but also androgen receptor (AR) antagonistic activity. Here, we describe the design, synthesis and evaluation of silicon-containing bis-phenol derivatives, with the objective
View All Related Papers

Protocols

GC Analysis of Phenols in Water

Analytical standard separation of various phenols for research and industrial applications.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service