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PHR1046

Ethylene glycol

Name: Ethylene glycol
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Monoethylene glycol, 1,2-Ethanediol

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About This Item

Linear Formula:

HOCH₂CH₂OH

CAS Number:

107-21-1

Molecular Weight:

62.07

Beilstein:

505945

EC Number:

203-473-3

MDL number:

MFCD00002885

UNSPSC Code:

41116107

eCl@ss:

39020501

PubChem Substance ID:

329823076

NACRES:

NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to USP 1265515

vapor density

2.1 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

CofA

current certificate can be downloaded

autoignition temp.

752 °F

expl. lim.

15.3 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.431 (lit.)

bp

195-198 °C

mp

−13 °C (lit.)

density

1.113 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Related Categories

Analytical Reference Standards

Certified Reference Materials

Pharmacopeia & Metrological Institute Standards

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ethylene glycol can also be produced from fossil fuels (petroleum, natural gas and coal) and biomass-derived resources. It is a polyol having a wide range of industrial applications.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Ethylene glycol may be used as a standard in the determination of ethylene glycol present in serum samples using gas chromatography (GC).

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2089 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictograms

GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302,H373

Precautionary Statements

P260 - P264 - P270 - P301 + P312 - P314 - P501

Hazard Classifications

Acute Tox. 4 Oral - STOT RE 2 Oral

Target Organs

Kidney

WGK

WGK 1

Flash Point(F)

239.0 °F

Flash Point(C)

115 °C

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If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
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The lot specific COA document can be found by entering the lot number above under the "Documents" section.
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
What is the molarity of ethylene glycol?
Ethylene glycol is 17.93M. This is calculated using the density (1.113 g/ml) and the molecular weight (62.07 g/mol). If the product is less than 100% pure, correct for the purity.
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Gas-chromatographic determination of ethylene glycol in serum

Porter H.W and Auansakul aA

Clinical Chemistry, 28, 75-78 (1982)

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