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PHL89151

Acetoxyvalerenic acid

phyproof® Reference Substance

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Synonym(s):
Acetylvalerenolic acid
Empirical Formula (Hill Notation):
C17H24O4
CAS Number:
Molecular Weight:
292.37
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

primary reference standard

product line

phyproof® Reference Substance

Assay

≥95.0% (HPLC)

manufacturer/tradename

PhytoLab

application(s)

food and beverages

format

neat

storage temp.

−20°C

SMILES string

C[C@@H]1CC[C@@H](\C=C(/C)C(O)=O)C2=C(C)C[C@@H](OC(C)=O)[C@H]12

InChI

1S/C17H24O4/c1-9-5-6-13(7-11(3)17(19)20)15-10(2)8-14(16(9)15)21-12(4)18/h7,9,13-14,16H,5-6,8H2,1-4H3,(H,19,20)/b11-7+/t9-,13+,14-,16+/m1/s1

InChI key

VBBXZFLAYWAXSK-HYJCDKNOSA-N

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General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application

  • Acetoxyvalerenic acid in bioactive spectral analysis: Research demonstrated the use of ATR-FTIR spectroscopy for quality control of Valerianae Radix, potentially including compounds like Acetoxyvalerenic acid, to ensure the bioactive natural compounds meet pharmaceutical standards (Nikzad-Langerodi et al., 2018).
  • Pharmacokinetics of valerenic derivatives: A study on the pharmacokinetics of valerenic acid, closely related to Acetoxyvalerenic acid, in older women illustrates its bioavailability and potential as a GABAergic activity modulator, which is crucial for developing sedative pharmaceuticals (Anderson et al., 2010).
  • Enhancement of sesquiterpenic acids in Valeriana officinalis: Research showed that root colonization by arbuscular mycorrhizal fungi increases the concentrations of sesquiterpenic acids, including potentially Acetoxyvalerenic acid, emphasizing its importance in valerian derivative biochemical studies (Nell et al., 2010).
  • Acetoxyvalerenic acid in blood-brain barrier studies: A study investigated the transport of GABAA receptor modulators across the blood-brain barrier, relevant for compounds like Acetoxyvalerenic acid, providing key insights into its neuropharmacological applications (Neuhaus et al., 2008).
  • GABAA receptor modulation by valerian extracts: The modulation of GABAA receptors by valerian extracts was found to be correlated with the content of valerenic acid, which includes derivatives like Acetoxyvalerenic acid, indicating its potential use in natural sedative compound research (Trauner et al., 2008).

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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