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P1847

Sigma-Aldrich

Potassium gluconate

97.0-103.0% dry basis, meets USP testing specifications

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Synonym(s):
Potassium D-gluconate, 2,3,4,5,6-Pentahydroxycaproic acid potassium salt, D-Gluconic acid potassium salt
Empirical Formula (Hill Notation):
C6H11KO7
CAS Number:
299-27-4
Molecular Weight:
234.25
Beilstein:
3919448
EC Number:
206-074-2
MDL number:
MFCD00064211
UNSPSC Code:
12352201
PubChem Substance ID:
24898248
NACRES:
NA.21

grade

anhydrous

Quality Level

200

Agency

USP/NF
meets USP testing specifications

Assay

97.0-103.0% dry basis

form

powder

impurities

≥1.0 % (v/v) reducing substances

color

white

mp

183 °C (dec.) (lit.)

solubility

water: soluble

application(s)

pharmaceutical (small molecule)

SMILES string

[K+].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

InChI

1S/C6H12O7.K/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1

InChI key

HLCFGWHYROZGBI-JJKGCWMISA-M

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Application

Potassium gluconate has been used as:
  • a component in intracellular solution (1x) for electrophysiology recordings in cultured neurons
  • as a component of solution for electroporation of neurons
  • in the preparation of intracellular pipette solution

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Optogenetic stimulation and recording of primary cultured neurons with spatiotemporal control
Barral J and Reyes AD
Bio-protocol, 7(12) (2017)
In vivo functional mapping of a cortical column at single-neuron resolution
Tischbirek CH, et al.
Cell Reports, 27(5), 1319-1326 (2019)
Assembly and operation of the autopatcher for automated intracellular neural recording in vivo
Kodandaramaiah SB, et al.
Nature Protocols, 11(4), 634-634 (2016)
Carsten H Tischbirek et al.
Cell reports, 27(5), 1319-1326 (2019-05-03)
The cerebral cortex is organized in vertical columns that contain neurons with similar functions. The cellular micro-architecture of such columns is an essential determinant of brain dynamics and cortical information processing. However, a detailed understanding of columns is incomplete, even
Esther Krook-Magnuson et al.
The Journal of physiology, 593(10), 2379-2388 (2015-03-11)
The dentate gyrus is a region subject to intense study in epilepsy because of its posited role as a 'gate', acting to inhibit overexcitation in the hippocampal circuitry through its unique synaptic, cellular and network properties that result in relatively
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