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P1722

Sigma-Aldrich

Potassium citrate tribasic monohydrate

meets USP testing specifications

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Synonym(s):
Citric acid tripotassium salt, Tripotassium citrate
Linear Formula:
HOC(COOK)(CH2COOK)2 · H2O
CAS Number:
6100-05-6
Molecular Weight:
324.41
Beilstein:
3924344
EC Number:
231-905-0
MDL number:
MFCD00150442
UNSPSC Code:
12352100
PubChem Substance ID:
57654504
NACRES:
NA.21

Agency

USP/NF
meets USP testing specifications

Quality Level

200

form

crystals

mp

275 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

O.[K+].[K+].[K+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3K.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;1H2/q;3*+1;/p-3

InChI key

PJAHUDTUZRZBKM-UHFFFAOYSA-K

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General description

Potassium citrate tribasic monohydrate (KCTM) is a potassium salt that has been reported to be efficient in forming aqueous two-phase system (ATPS) with UCON 50-HB-5100, a random copolymer. This product is a high quality pharmacopoeia product that meets the testing specifications of USP (United States Pharmacopoeia). It can be employed in research and pilot studies.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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(Liquid+ liquid) equilibria of polymer-salt aqueous two-phase systems for laccase partitioning: UCON 50-HB-5100 with potassium citrate and (sodium or potassium) formate at 23?C.
Lladosa E, et al.
The Journal of Chemical Thermodynamics, 55, 166-171 (2012)
Naim M Maalouf et al.
The Journal of clinical endocrinology and metabolism, 96(12), 3733-3740 (2011-10-07)
Dietary intake of animal proteins is associated with an increase in urinary calcium and nephrolithiasis risk. We tested the hypothesis that the acid load imposed by dietary proteins causes this hypercalciuria. In a short-term crossover metabolic study, an alkali salt
Donna J Claes et al.
Pediatric nephrology (Berlin, Germany), 27(11), 2031-2038 (2012-01-28)
Cystinuria is a relatively uncommon cause of pediatric stone disease, but has significant morbidity if not properly controlled because of its significant stone recurrence rate. Cystinuria is caused by the inability of the renal tubules to reabsorb filtered cystine, which
Pierre Cochat et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 27(5), 1729-1736 (2012-05-02)
Primary hyperoxaluria Type 1 is a rare autosomal recessive inborn error of glyoxylate metabolism, caused by a deficiency of the liver-specific enzyme alanine:glyoxylate aminotransferase. The disorder results in overproduction and excessive urinary excretion of oxalate, causing recurrent urolithiasis and nephrocalcinosis.
Khashayar Sakhaee et al.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 8(1), 67-72 (2011-06-28)
Patients undergoing Roux-en-Y gastric bypass (RYGB) surgery are prone to developing bone loss and kidney stones. The goal of the present study was to test the hypothesis that an effervescent formulation of potassium calcium citrate (PCC) would avert metabolic complications
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