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P0380

Sigma-Aldrich

L-Proline

≥99% (HPLC), ReagentPlus®

Synonym(s):

(S)-Pyrrolidine-2-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C5H9NO2
CAS Number:
Molecular Weight:
115.13
Beilstein:
80810
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

product name

L-Proline, ReagentPlus®, ≥99% (HPLC)

Quality Level

product line

ReagentPlus®

Assay

≥99% (HPLC)

form

powder

impurities

L-Hydroxyproline, free

color

white

mp

228 °C (dec.) (lit.)

application(s)

detection

SMILES string

OC(=O)[C@@H]1CCCN1

InChI

1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1

InChI key

ONIBWKKTOPOVIA-BYPYZUCNSA-N

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Application

L-Proline has been used:
  • As a supplement during the preparation of chondrogenic medium and synthetic dextrose minimal medium (SD).
  • As a standard during the identification of metabolites in serum samples.
  • In a study to prepare L-proline-L-phenylalanine (L-Pro-L-Phe) mixture in aqueous acetonitrile.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Andrew Davison
Eureka: Biochemistry & Metabolism, 2015, 76-76 (2015)
Metabolomic insights into system-wide coordination of vertebrate metamorphosis.
Ichu TA, et al.
BMC Developmental Biology, 14(1), 1-1 (2014)
Proline: a multifunctional amino acid
La' szlo' Szabados and Arnould Savoure
Trends in Plant Science, 1-9 (2009)
Mieczysław Sajewicz et al.
Journal of chromatographic science, 53(1), 31-37 (2014-03-05)
We employ the achiral liquid chromatography with diode array, evaporative light scattering and mass spectrometric detection (HPLC-DAD, HPLC-ELSD and LC-MS) to assess structural instability (understood as spontaneous oscillatory chiral conversion and spontaneous oscillatory condensation) of the two pairs of amino
Natasja Leth Joergensen et al.
BioResearch open access, 4(1), 109-114 (2015-08-27)
Cartilage regeneration is a fast growing field that combines biotechnology and molecular techniques in creating new tissue mimicking the native microenvironment. Human embryonic stem cells (hESCs) are a highly potent cell source for cartilage regeneration owing to their infinite proliferation

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The List group focuses on the development of new concepts in catalysis. Since 1999, this research group has pioneered the development of organocatalysis as the third pillar of stereoselective catalysis, along side biocatalysis and transition metal catalysis.

Chromatograms

application for HPLC

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