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N5000

Sigma-Aldrich

Naphthol AS-MX phosphate disodium salt

≥98% purity (HPLC), powder

Synonym(s):

Naphthol AS-MX phosphate disodium salt, phosphatase substratesodium 3-(2,4-dimethylphenylcarbamoyl)naphthalen-2-yl phosphate

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About This Item

Linear Formula:
C19H16NO5PNa2
CAS Number:
Molecular Weight:
415.29
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

Naphthol AS-MX phosphate disodium salt, phosphatase substrate

Quality Level

Assay

≥98.0% (HPLC)

form

powder

solubility

water: 100 mg/mL, clear to hazy

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

[Na+].[Na+].Cc1ccc(NC(=O)c2cc3ccccc3cc2OP([O-])([O-])=O)c(C)c1

InChI

1S/C19H18NO5P.2Na/c1-12-7-8-17(13(2)9-12)20-19(21)16-10-14-5-3-4-6-15(14)11-18(16)25-26(22,23)24;;/h3-11H,1-2H3,(H,20,21)(H2,22,23,24);;/q;2*+1/p-2

InChI key

IHRJBGLDOBEMPR-UHFFFAOYSA-L

Application

Naphthol AS-MX phosphate disodium salt is intended for use as a substrate for the histochemical demonstration of alkaline phosphatase activities.

Substrates

Substrate for the histochemical demonstration of acid and alkaline phosphatase.

related product

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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CYTOCHEMICAL DEMONSTRATION OF ACID PHOSPHATASE IN HEMATOPOIETIC CELLS IN HEALTH AND IN VARIOUS HEMATOLOGICAL DISORDERS USING AZO DYE TECHNIQUES.
L S KAPLOW et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 12, 805-811 (1964-11-01)
D M Boorsma
Histochemistry, 80(2), 103-106 (1984-01-01)
A novel method for immunoenzymatic double staining was developed, using primary antibodies directly labeled with either horseradish peroxidase or alkaline phosphatase. The enzyme-antibody conjugates were applied simultaneously on sections of human tonsil. Intracytoplasmic antigens like immunoglobulins and light chains could
S J Harper et al.
Journal of clinical pathology, 45(2), 114-119 (1992-02-01)
The development of a technique for simultaneous in situ hybridisation for native mRNA and conventional immunofluorescence for cytoplasmic antigens in routine pathology specimens. Cocktails of synthetic deoxyoligonucleotides coding for immunoglobulin J chain and kappa light chain were 3' end labelled
Efficacy of freeze-dried platelet-rich plasma in bone engineering.
Nakatani Y
Archives of Oral Biology, 73, 172-172 (2017)
Stathmin is expressed by the proliferating hepatocytes during liver regeneration.
Rowlands DC
Clinical Molecular Pathology, 48, M88-M88 (1995)

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