Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

N0800000

Nikethamide

European Pharmacopoeia (EP) Reference Standard

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
N,N-Diethylnicotinamide, Nicotinic acid diethylamide, ‘Nikethamide’
Empirical Formula (Hill Notation):
C10H14N2O
CAS Number:
59-26-7
Molecular Weight:
178.23
Beilstein:
5743
MDL number:
MFCD00006386
UNSPSC Code:
41116107
PubChem Substance ID:
329818462
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

nikethamide

manufacturer/tradename

EDQM

refractive index

n20/D 1.524 (lit.)

bp

296-300 °C (lit.)

mp

23 °C (lit.)

density

1.06 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCN(CC)C(=O)c1cccnc1

InChI

1S/C10H14N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3

InChI key

NCYVXEGFNDZQCU-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Nikethamide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301,H319

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2

WGK

WGK 1

Flash Point(F)

235.4 °F

Flash Point(C)

113 °C

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Determination of nikethamide and N-ethylnicotinamide in the blood and urine of greyhounds.
Lewis J H.
Journal of Chromatography A, 172, 295-302 (1979)
Lili Chen et al.
Journal of pharmaceutical and biomedical analysis, 43(5), 1757-1762 (2007-02-10)
Nikethamide and lidocaine are often requested to be quantified simultaneously in forensic toxicological analysis. A simple reversed-phase high performance liquid chromatography (RP-HPLC) method has been developed for their simultaneous determination in human blood and cerebrospinal fluid. The method involves simple
Nathaly Reyes-Garcés et al.
Journal of chromatography. A, 1374, 40-49 (2014-12-03)
Simple, fast and efficient sample preparation approaches that allow high-throughput isolation of various compounds from complex matrices are highly desired in bioanalysis. Particularly sought are methods that can, without sacrificing time, easily remove matrix interferences capable of inducing ionization suppression/enhancement

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service