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Merck
CN

M8911

Methyl 4-hydroxybenzoate

analytical standard

Synonym(s):

p-Hydroxybenzoic acid methyl ester, Methyl paraben, NIPAGIN

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About This Item

Linear Formula:
HOC6H4CO2CH3
CAS Number:
99-76-3
Molecular Weight:
152.15
UNSPSC Code:
51452201
NACRES:
NA.77
PubChem Substance ID:
24897298
EC Number:
202-785-7
Beilstein/REAXYS Number:
509801
MDL number:
MFCD00002352

Key Documents

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Product Name

Methyl 4-hydroxybenzoate, analytical standard

InChI key

LXCFILQKKLGQFO-UHFFFAOYSA-N

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

SMILES string

COC(=O)c1ccc(O)cc1

grade

analytical standard

assay

98.0-102.0%

form

solid

packaging

vial of 200 mg

mp

125-128 °C (lit.)

Quality Level

200

Gene Information

rat ... Ar(24208)

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Packaging

Supplied in amber screw-cap vials
Bottomless glass bottle. Contents are inside inserted fused cone.

Application

Methyl 4-hydroxybenzoate has been used as an internal standard for the determination of trans-10-hydroxy-2-decenoic acid (10-HDA).

pictograms

Environment
GHS09

hcodes

H411

Hazard Classifications

Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

334.4 °F

flash_point_c

168 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
099K8725
097K5005
114K8801
075K88031
075K8803

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Comparison of UPLC and HPLC for determination of trans-10-hydroxy-2-decenoic acid content in royal jelly by ultrasound-assisted extraction with internal standard
Zhou J, et al.
Chromatographia, 66(3-4), 185-190 (2007)
Optimized determination method for trans-10-hydroxy-2-decenoic acid content in royal jelly by high-performance liquid chromatography with an internal standard
Zhou J, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 90(1), 244-249 (2007)
Kyung-Jin Min et al.
Aging cell, 7(2), 199-206 (2008-01-29)
Reduced insulin/insulin-like growth factor (IGF) signaling may be a natural way for the reduction of dietary nutrients to extend lifespan. While evidence challenging this hypothesis is accumulating with Caenorhabditis elegans, for Drosophila melanogaster it is still thought that insulin/IGF and
Gabriela Oliveira et al.
International journal of pharmaceutics, 435(1), 38-49 (2012-05-29)
Simple topical formulations which include volatile components, such as gels or sprays, are appealing from a cosmetic perspective. However, complex formulation effects may result from the use of volatile excipients in topical formulations, particularly when applied at clinically relevant doses
Ismail I Hewala et al.
Talanta, 88, 623-630 (2012-01-24)
Simple methods for HPTLC peak purity assessment and identification of the HPTLC peaks were presented. The spectrodensitograms - selected at different time intervals across the elution time of the HPTLC peak - were extracted and digital algorithms for manipulating the
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