M8054
Manganese(II) chloride tetrahydrate
meets USP testing specifications
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Manganese chloride hydrate, Manganese chloride tetrahydrate, MnCl2.4H2O
MnCl2 · 4H2O
Recommended Products
Agency
USP/NF
meets USP testing specifications
Quality Level
Assay
98.0-101.0% dry basis
form
flakes
mp
58 °C (lit.)
application(s)
pharmaceutical (small molecule)
SMILES string
Cl[Mn]Cl.[H]O[H].[H]O[H].[H]O[H].[H]O[H]
InChI
1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2
InChI key
CNFDGXZLMLFIJV-UHFFFAOYSA-L
Related Categories
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2
Target Organs
Brain
WGK
WGK 2
Flash Point(F)
does not flash
Flash Point(C)
does not flash
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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NMR in biomedicine, 25(12), 1360-1368 (2012-05-11)
The aim of this study was to provide data on the dose dependence of manganese-enhanced MRI (MEMRI) in the visual pathway of experimental rats and to study the toxicity of MnCl₂ to the retina. Sprague-Dawley rats were intravitreally injected with
Toxicology letters, 214(3), 288-295 (2012-09-22)
The role of normal cellular prion protein (PrP) remains to be fully elucidated; however, the protein is crucial for the infection and progression of prion diseases. Recent evidence indicates that PrP is a metalloprotein since the octapeptide repeat sequences in
Neurotoxicology, 35, 121-128 (2013-01-15)
Chronic exposure to Mn results in the development of a neurological disorder known as manganism characterized by neurological deficits resembling that seen in Parkinsonism. Although dopaminergic neurons within the nigrostriatal pathway appear intact, Mn-induced irregularities in DA transmission have been
Medical physics, 40(4), 042502-042502 (2013-04-06)
Manganese(II) is employed as a contrast agent with magnetic resonance imaging (MRI) for study of neuronal activation in rats and mice. However, at the concentrations required for MRI, Mn may induce pharmacological or toxic effects. Positron emission tomography (PET) imaging
NeuroImage, 64, 693-702 (2012-09-11)
The impairment of axonal transport by overexpression or hyperphosphorylation of tau is well documented for in vitro conditions; however, only a few studies on this phenomenon have been conducted in vivo, using invasive procedures, and with contradictory results. Here we
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