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M2523

Supelco

Mebendazole

analytical standard, ≥98% (HPLC)

Synonym(s):

5-Benzoyl-2-benzimidazolecarbamic acid methyl ester, Mebendazol, Methyl N-(5-benzoyl-1H-benzimidazol-2-yl)carbamate

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About This Item

Empirical Formula (Hill Notation):
C16H13N3O3
CAS Number:
31431-39-7
Molecular Weight:
295.29
Beilstein:
759809
EC Number:
250-635-4
MDL number:
MFCD00057872
UNSPSC Code:
41116107
PubChem Substance ID:
329817943
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥98% (HPLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccccc3

InChI

1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)

InChI key

OPXLLQIJSORQAM-UHFFFAOYSA-N

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General description

Mebendazole is a benzimidazole carbamate derivative, which is an anthelmintic agent.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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The Antimicrobial Drugs (2000)
Peter Nygren et al.
Journal of cancer research and clinical oncology, 139(12), 2133-2140 (2013-10-19)
In the present study, we screened a compound library containing 1,600 clinically used compounds with the aim to identify compounds, which potentially could be repositioned for colon cancer therapy. Two established colon cancer cell lines were tested using the fluorometric
Sara Carlert et al.
Molecular pharmaceutics, 9(10), 2903-2911 (2012-09-08)
The purpose of this study was to investigate in vivo intestinal precipitation of a model drug mebendazole, a basic BCS class II drug, using dogs with intestinal stomas for administration or sampling. After oral administration of a solution with an
Monica Longo et al.
Reproductive toxicology (Elmsford, N.Y.), 36, 78-87 (2013-01-05)
Filarial diseases affect millions of people in poverty-stricken areas. In 2011, an investigation of the potential of flubendazole as a safe, highly efficacious, and field-usable macrofilaricidal drug was begun by Drug for Neglected Diseases initiative. As part of the preclinical
Sivanesan Dakshanamurthy et al.
Journal of medicinal chemistry, 55(15), 6832-6848 (2012-07-12)
The most effective way to move from target identification to the clinic is to identify already approved drugs with the potential for activating or inhibiting unintended targets (repurposing or repositioning). This is usually achieved by high throughput chemical screening, transcriptome
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