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M1851000

Metronidazole benzoate

European Pharmacopoeia (EP) Reference Standard

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Synonym(s):
2-Methyl-5-nitro-1H-imidazole-1-ethyl benzoate
Empirical Formula (Hill Notation):
C13H13N3O4
CAS Number:
Molecular Weight:
275.26
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

metronidazole

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C13H13N3O4/c1-10-14-9-12(16(18)19)15(10)7-8-20-13(17)11-5-3-2-4-6-11/h2-6,9H,7-8H2,1H3

InChI key

CUUCCLJJOWSASK-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Metronidazole benzoate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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B Bloch et al.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 67(12), 455-457 (1985-03-23)
Metronidazole tablets, benzoyl metronidazole suspension and tinidazole tablets each given as a single 2 g bolus dose in an open controlled prospective study were found to be effective forms of treatment for Trichomonas vaginalis vaginitis. The cure rates on wet
[HPLC determination of benzoylmetronidazole and metronidazole in biological materials].
J Avramova
Die Pharmazie, 43(6), 436-436 (1988-06-01)
G Takács
Therapia Hungarica (English edition), 40(4), 189-191 (1992-01-01)
Klion suspension was given to 42 girl and woman patients suffering from vaginal trichomoniasis. Negativity for Trichomonas was recorded in 73.8% of the cases in response to the first 10-day cure, and in 90.5% of the patients following repeated cures.
J A Ogunbanwo et al.
FEMS immunology and medical microbiology, 30(1), 73-83 (2001-02-15)
The trypanosomostatic and trypanosomicidal effects of four anti-protozoal drugs, namely halofantrine hydrochloride, chloroquine phosphate, benzoylmetronidazole and pyrimethamine, on species of trypanosomes, viz. Trypanosoma brucei brucei (MBOS/NG/94/NITR) Bassa strain, T. congolense (MBOS/NG/93/NVRI) Zaria strain and T. brucei gambiense (MHOM/NG/92/NITR) Abraka strain
S M Ross et al.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 63(15), 566-567 (1983-04-09)
Antenatal patients free of Trichomonas vaginalis vaginal infection were compared with infected patients, half of whom were treated and half left untreated. The treated group was given benzoylmetronidazole 50 ml (2 g metronidazole equivalent) as a single dose. The mode

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