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About This Item
Empirical Formula (Hill Notation):
C13H13N3O4
CAS Number:
Molecular Weight:
275.26
UNSPSC Code:
41116107
NACRES:
NA.24
Product Name
Metronidazole benzoate, European Pharmacopoeia (EP) Reference Standard
SMILES string
[N+](=O)([O-])c1[n](c(nc1)C)CCOC(=O)c2ccccc2
InChI
1S/C13H13N3O4/c1-10-14-9-12(16(18)19)15(10)7-8-20-13(17)11-5-3-2-4-6-11/h2-6,9H,7-8H2,1H3
InChI key
CUUCCLJJOWSASK-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
metronidazole
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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Application
Metronidazole benzoate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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S M Ross et al.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 63(15), 566-567 (1983-04-09)
Antenatal patients free of Trichomonas vaginalis vaginal infection were compared with infected patients, half of whom were treated and half left untreated. The treated group was given benzoylmetronidazole 50 ml (2 g metronidazole equivalent) as a single dose. The mode
B Bloch et al.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 67(12), 455-457 (1985-03-23)
Metronidazole tablets, benzoyl metronidazole suspension and tinidazole tablets each given as a single 2 g bolus dose in an open controlled prospective study were found to be effective forms of treatment for Trichomonas vaginalis vaginitis. The cure rates on wet
G Takács
Therapia Hungarica (English edition), 40(4), 189-191 (1992-01-01)
Klion suspension was given to 42 girl and woman patients suffering from vaginal trichomoniasis. Negativity for Trichomonas was recorded in 73.8% of the cases in response to the first 10-day cure, and in 90.5% of the patients following repeated cures.
[HPLC determination of benzoylmetronidazole and metronidazole in biological materials].
J Avramova
Die Pharmazie, 43(6), 436-436 (1988-06-01)
J A Ogunbanwo et al.
FEMS immunology and medical microbiology, 30(1), 73-83 (2001-02-15)
The trypanosomostatic and trypanosomicidal effects of four anti-protozoal drugs, namely halofantrine hydrochloride, chloroquine phosphate, benzoylmetronidazole and pyrimethamine, on species of trypanosomes, viz. Trypanosoma brucei brucei (MBOS/NG/94/NITR) Bassa strain, T. congolense (MBOS/NG/93/NVRI) Zaria strain and T. brucei gambiense (MHOM/NG/92/NITR) Abraka strain
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