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M0960000

Methionine

Name: Methionine
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

L-Methionine, (S)-2-Amino-4-(methylmercapto)butyric acid, L-2-Amino-4-(methylthio)butanoic acid

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About This Item

Linear Formula:

CH₃SCH₂CH₂CH(NH₂)CO₂H

CAS Number:

63-68-3

Molecular Weight:

149.21

Beilstein:

1722294

MDL number:

MFCD00063097

UNSPSC Code:

41116107

PubChem Substance ID:

329817843

NACRES:

NA.24

grade

pharmaceutical primary standard

API family

methionine & derivatives

manufacturer/tradename

EDQM

mp

284 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CSCC[C@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

InChI key

FFEARJCKVFRZRR-BYPYZUCNSA-N

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Analytical Reference Standards

Pharmacopeia & Metrological Institute Standards

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Methionine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.

Description

Pricing

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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The in vivo sparing of methionine by cysteine in sulfur amino acid requirements in animal models and adult humans.

Ronald O Ball et al.

The Journal of nutrition, 136(6 Suppl), 1682S-1693S (2006-05-17)

Sulfur amino acid metabolism has been receiving increased attention because of the link to chronic diseases such as cardiovascular disease, Alzheimer's disease, and diabetes. In addition, the role of cysteine and optimal intakes for physiological substrates such as glutathione are

Planar scintigraphy with 123I/99mTc-sestamibi, 99mTc-sestamibi SPECT/CT, 11C-methionine PET/CT, or selective venous sampling before reoperation of primary hyperparathyroidism?

Camilla Schalin-Jäntti et al.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(5), 739-747 (2013-04-05)

All patients with primary hyperparathyroidism should undergo localization studies before reoperation, but it is not known which method is most accurate. The purpose of this prospective study was to compare the performance of planar scintigraphy with (123)I/(99m)Tc-sestamibi, (99m)Tc-sestamibi SPECT (SPECT/CT)

Deletion of the highly conserved N-glycan at Asn260 of HIV-1 gp120 affects folding and lysosomal degradation of gp120, and results in loss of viral infectivity.

Leen Mathys et al.

PloS one, 9(6), e101181-e101181 (2014-06-27)

N-linked glycans covering the surface of the HIV-1 glycoprotein gp120 are of major importance for the correct folding of this glycoprotein. Of the, on average, 24 N-linked glycans present on gp120, the glycan at Asn260 was reported to be essential

Analysis of metabolic profiles of bile acids in urine using a lipophilic anion exchanger and computerized gas-liquid chromatorgaphy-mass spectrometry.

B Almé et al.

Journal of lipid research, 18(3), 339-362 (1977-05-01)

A method is described for quantitative analysis of bile acids in urine. Urine is acidified and bile acids are extracted on an Amberlite XAD-2 column. Bile salts are converted to acids on an Amberlyst A-15 column and are separated into

Value of 11C-methionine PET in imaging brain tumours and metastases.

Andor W J M Glaudemans et al.

European journal of nuclear medicine and molecular imaging, 40(4), 615-635 (2012-12-13)

(11)C-methionine (MET) is the most popular amino acid tracer used in PET imaging of brain tumours. Because of its characteristics, MET PET provides a high detection rate of brain tumours and good lesion delineation. This review focuses on the role

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