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L6026

Sodium dodecyl sulfate

Name: Sodium dodecyl sulfate
Brand: SIAL

BioXtra, ≥99.0% (GC)

Synonym(s):

Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate

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About This Item

Linear Formula:

CH₃(CH₂)₁₁OSO₃Na

CAS Number:

151-21-3

Molecular Weight:

288.38

Beilstein:

3599286

EC Number:

205-788-1

MDL number:

MFCD00036175

UNSPSC Code:

12161900

eCl@ss:

39093306

PubChem Substance ID:

24896426

NACRES:

NA.21

biological source

synthetic (oragnic)

Quality Level

200

description

anionic

product line

BioXtra

Assay

≥99.0% (GC)

form

powder

mol wt

micellar avg mol wt 18,000

aggregation number

impurities

Insoluble matter, passes filter test

loss

≤0.5% loss on drying, HV, 20-25 °C

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

transition temp

cloud point >100 °C

solubility

H₂O: 0.1 M, clear, colorless

density

0.496 g/cm³

anion traces

chloride (Cl^-): ≤0.05%
phosphate (PO₄^3-): ≤0.0001%

cation traces

Al: ≤0.0005%
Ba: ≤0.0005%
Bi: ≤0.0005%
Ca: ≤0.001%
Cd: ≤0.0005%
Co: ≤0.0005%
Cr: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.02%
Li: ≤0.0005%
Mg: ≤0.0005%
Mn: ≤0.0005%
Mo: ≤0.0005%
Ni: ≤0.0005%
Pb: ≤0.0005%
Sr: ≤0.0005%
Zn: ≤0.0005%

absorption

≤0.05 at 280 in H₂O at 0.1 M
≤0.08 at 260 in H₂O at 0.1 M

HLB

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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Related Categories

Detergents - Anionic, Cationic, Zwitterionic, Anti-foaming

High-Purity Biochemicals and Reagents

General description

Sodium dodecyl sulfate (SDS) is a well-known anionic detergent widely used in scientific research to denature proteins′ secondary and tertiary structures. It consists of a 12-carbon non-polar chain with a negatively charged sulfate group at the end. SDS is instrumental in denaturing and solubilizing proteins, making it a fundamental component of procedures like polyacrylamide gel electrophoresis, where it helps determine protein molecular weights.Moreover, SDS acts as an organic sodium salt and serves dual roles as a detergent and a protein denaturant. Its distinctive feature is its anionic surfactant nature, characterized by a negative charge. This charge fosters interactions with proteins and lipids, leading to the creation of micellar structures. These micelles are essential for SDS′s capacity to effectively solubilize and stabilize proteins and lipids, enabling their detailed study and manipulation in scientific research. SDS′s amphipathic properties, stemming from a long-chain aliphatic group with an attached negatively charged sulfate, make it a valuable detergent for various biomolecular experiments and studies.

Application

Sodium dodecyl sulfate has been used as a:

surfactant to evaluate cytochrome c affinity by using surface plasmon resonance
surfactant in particle enhanced immunoassays to inhibit aggregation of particles and to enhance single microsphere coupling
biofilm-disrupting agent

Anionic detergent

Features and Benefits

Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
Tested for trace levels of Anions and Cations
High-purity product ideal for biochemical research purposes

Other Notes

For additional information on our range of Biochemicals, please complete this form.

comparable product

Product No.

Description

Pricing

Signal Word

Danger

Hazard Statements

H302,H315,H318,H412

Precautionary Statements

P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

WGK

WGK 2

Flash Point(F)

338.0 °F

Flash Point(C)

170 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Biomedical Devices and Their Applications (2013)

Evaluation of cytochrome c affinity to anionic phospholipids by means of surface plasmon resonance

Stepanov G, et al.

Febs Letters, 583(1), 97-100 (2009)

MrkD1P from Klebsiella pneumoniae strain IA565 allows for coexistence with Pseudomonas aeruginosa and protection from protease-mediated biofilm detachment.

Brandon M Childers et al.

Infection and immunity, 81(11), 4112-4120 (2013-08-28)

Biofilm formation and persistence are essential components for the continued survival of pathogens inside the host and constitute a major contributor to the development of chronic wounds with resistance to antimicrobial compounds. Understanding these processes is crucial for control of

Using highly carboxylated microspheres to simplify immunoassays and enhance diffusional mixing in a microfluidic device.

Lonnie J Lucas et al.

Colloids and surfaces. B, Biointerfaces, 49(2), 106-111 (2006-04-20)

Manufacturers of latex immunoassays have typically added surfactants to improve detection sensitivity and prevent non-specific aggregation of microspheres, which may cause both false positives and negatives during diagnostic testing. There is also growing interest in conducting immunoassays in smaller volumes

Bacterial effector modulation of host E3 ligase activity suppresses PAMP-triggered immunity in rice.

Kazuya Ishikawa et al.

Nature communications, 5, 5430-5430 (2014-11-13)

Pathogen effector proteins are delivered to host cells to suppress plant immunity. However, the mechanisms by which effector proteins function are largely unknown. Here we show that expression of XopP(Xoo), an effector of rice pathogen Xanthomonas oryzae pv. oryzae, in

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