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Merck
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Key Documents

Safety Information

L3900

Sigma-Aldrich

2,6-Lutidine

ReagentPlus®, 98%

Synonym(s):

2,6-Dimethylpyridine

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About This Item

Empirical Formula (Hill Notation):
C7H9N
CAS Number:
Molecular Weight:
107.15
Beilstein:
105690
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

Quality Level

product line

ReagentPlus®

Assay

98%

form

liquid

refractive index

n20/D 1.497 (lit.)

bp

143-145 °C ((lit.))
143-145 °C (lit.)

mp

-6 °C
−6 °C (lit.)

density

0.92  g/mL at 25 °C ((lit.))
0.92 g/mL at 25 °C (lit.)

SMILES string

CCCCCCCCCCCC(=O)ON1C(=O)CCC1=O
Cc1cccc(C)n1

InChI

1S/C16H27NO4/c1-2-3-4-5-6-7-8-9-10-11-16(20)21-17-14(18)12-13-15(17)19/h2-13H2,1H3
1S/C7H9N/c1-6-4-3-5-7(2)8-6/h3-5H,1-2H3

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Show Differences

1 of 4

This Item
810800P800811C800811O
18:1 DG 1-2-dioleoyl-sn-glycerol, chloroform

800811C

18:1 DG

18:1 DG Avanti Research™ - A Croda Brand

800811O

18:1 DG

assay

>99% (TLC)

assay

>99% (TLC)

assay

>99% (TLC)

assay

>99% (TLC)

packaging

pkg of 1 × 5 mg (810811P-5mg)

packaging

pkg of 1 × 10 mg (810800P-10mg)

packaging

pkg of 1 × 5 mL (800811C-10mg), pkg of 1 × 5 mL (800811C-25mg), pkg of 1 × 8 mL (800811C-200mg)

packaging

pkg of 1 × 10 mg (with screw cap (800811O-10mg)), pkg of 2 × 100 mg (with screw cap (800811O-200mg)), pkg of 5 × 100 mg (with screw cap 800811O-500mg), pkg of 1 × 25 mg (with screw cap (800811O-25mg))

form

powder

form

powder

form

liquid

form

liquid

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

manufacturer/tradename

Avanti Polar Lipids 810811P

manufacturer/tradename

Avanti Polar Lipids 810800P

manufacturer/tradename

Avanti Polar Lipids 800811C

manufacturer/tradename

Avanti Polar Lipids

Application

2,6-Lutidine can be used as a base for the oxidation of α-CF3 alcohols to the corresponding carbonyl compounds in the presence of 4-acetamido-2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate (Bobbitt′s salt) as oxidation reagent.[1]
It can be used:
  • As a promoter for catalytic asymmetric fluorination of α-cyanophosphonates in the presence of chiral Pd(II)-bisphosphine complexes.[2]
  • In combination with tert-butyldimethylsilyl triflate for the protection of tertiary alcohols and unreactive secondary alcohols.[3]
  • In combination with triethylsilyl trifluoromethanesulfonate for the conversion of acetals to the corresponding aldehydes in dichloromethane followed by workup in water.[4]

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

91.4 °F

Flash Point(C)

33 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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    Pd (II)-Catalyzed Asymmetric Fluorination of ?-Aryl-?-cyanophosphonates with the Aid of 2, 6-Lutidine.
    Moriya K I, et al.
    Synlett, 2007(07), 1139-1142 (2007)
    Studies with trialkylsilyltriflates: new syntheses and applications.
    Corey E J, et al.
    Tetrahedron Letters, 22(36), 3455-3458 (1981)
    Unexpected Highly Chemoselective Deprotection of the Acetals from Aldehydes and Not Ketones: TESOTf? 2, 6-Lutidine Combination.
    Fujioka H, et al.
    Journal of the American Chemical Society, 126(38), 11800-11801 (2004)
    Synthesis of 4-acetamido-2, 2, 6, 6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate and 4-acetamido-(2, 2, 6, 6-tetramethyl-piperidin-1-yl) oxyl and their use in oxidative reactions.
    Mercadante M A, et al.
    Nature Protocols, 8(4), 666-666 (2013)
    Elisabetta Fanizza et al.
    International journal of molecular sciences, 20(13) (2019-06-30)
    The low photostability of conventional organic dyes and the toxicity of cadmium-based luminescent quantum dots have prompted the development of novel probes for in vitro and in vivo labelling. Here, a new fluorescent lanthanide probe based on silica nanoparticles is

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