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I0775000

Isosorbide dinitrate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

ISDN

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About This Item

Empirical Formula (Hill Notation):
C6H8N2O8
CAS Number:
87-33-2
Molecular Weight:
236.14
NACRES:
NA.24
PubChem Substance ID:
329815326
UNSPSC Code:
41116107
MDL number:
MFCD00868238

Key Documents

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Product Name

Isosorbide dinitrate, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C6H8N2O8/c9-7(10)15-3-1-13-6-4(16-8(11)12)2-14-5(3)6/h3-6H,1-2H2

SMILES string

[H][C@@]1([C@@]([H])(O[N+]([O-])=O)CO2)[C@@]2([H])[C@]([H])(O[N+]([O-])=O)CO1

InChI key

MOYKHGMNXAOIAT-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

isosorbide

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

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Application

Isosorbide dinitrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Warning

hcodes

H207,H302

Hazard Classifications

Acute Tox. 4 Oral - Desen. Expl. 3

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Ryo Kurokawa et al.
Medicine, 98(19), e15538-e15538 (2019-05-15)
To compare coronary artery luminal enhancement in coronary computed tomography angiography (CCTA) between ventral and dorsal region-of-interest (ROI) bolus tracking in the descending aorta.The records of 165 consecutive patients who underwent CCTA with non-helical acquisition from July 2017 to March
Stephane Fournier et al.
Journal of the American Heart Association, 9(24), e017729-e017729 (2020-12-08)
Background Global fractional flow reserve (FFR) (ie, the sum of the FFR values in the 3 major coronary arteries) is a physiologic correlate of global atherosclerotic burden. The objective of the present study was to investigate the value of global
Eriko Maeda et al.
SpringerPlus, 4, 697-697 (2015-11-21)
To evaluate the degree of heart rate (HR) changes at rest (HRrest), during breath hold (HRtest), and during cardiac CT examinations (HRscan) in a large group of patients , and to derive and asses the feasibility of a predictive formula
Shinsuke Mori et al.
Journal of interventional cardiology, 2020, 7342732-7342732 (2020-09-29)
To compare feasibility and safety between ultrasound-guided and conventional distal transradial access (dTRA). Distal transradial access, a new technique for coronary angiography (CAG) and percutaneous coronary interventions (PCI), is safe and feasible and will become popular worldwide. Ultrasound-guided dTRA has
Giuseppe Di Gioia et al.
European heart journal, 41(17), 1665-1672 (2019-08-17)
Fractional flow reserve (FFR) has never been investigated in patients with reduced ejection fraction and associated coronary artery disease (CAD). We evaluated the impact of FFR on the management strategies of these patients and related outcomes. From 2002 to 2010
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